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Cytohesin 2 antibody (C-Term)
CYTH2
Reactivity: Human, Rat, Mouse, Sheep, Cow, Dog, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Cytohesin 2 Antibody
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Target
See all Cytohesin 2 (CYTH2) Antibodies
Cytohesin 2 (CYTH2)
Binding Specificity
All epitopes for Cytohesin 2 antibodies
C-Term
Reactivity
Human, Rat, Mouse, Sheep, Cow, Dog, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)
Host
All hosts for Cytohesin 2 antibodies
Rabbit
Clonality
All clonalities for Cytohesin 2 antibodies
Polyclonal
Conjugate
All conjugates for Cytohesin 2 antibodies
This Cytohesin 2 antibody is un-conjugated
Application
All applications for Cytohesin 2 antibodies
Western Blotting (WB)
Sequence
GRVKTWKRRW FILTDNCLYY FEYTTDKEPR GIIPLENLSI REVDDPRKPN
Predicted Reactivity
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
Characteristics
This is a rabbit polyclonal antibody against CYTH2. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human CYTH2
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for Cytohesin 2
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Target
Cytohesin 2 (CYTH2)
Alternative Name
CYTH2 (CYTH2 Products )
Synonyms
ARNO antibody, CTS18 antibody, CTS18.1 antibody, PSCD2 antibody, PSCD2L antibody, SEC7L antibody, Sec7p-L antibody, Sec7p-like antibody, CLM2 antibody, Pscd2 antibody, Arno antibody, Sec7 antibody, Sec7B antibody, pscd2 antibody, MGC84366 antibody, CYTH2 antibody, cyth2 antibody, cytohesin 2 antibody, cytohesin-2 antibody, cytohesin 2 L homeolog antibody, si:dkey-283b15.4 antibody, CYTH2 antibody, PTRG_08834 antibody, Cyth2 antibody, cyth2.L antibody, cyth2 antibody, si:dkey-283b15.4 antibody
Background
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83 % homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. Alias Symbols: ARNO, CTS18, CTS18.1, PSCD2, PSCD2L, SEC7L, Sec7p-L, Sec7p-like Protein Interaction Partner: CCDC120, UBC, ARF6, GNAQ, PNPLA2, DYT10, MAPK6, APC, IPCEF1, ATP6V0A2, CYTIP, ARFGAP1, TRIM23, ITGB2, PRKCG, PRKCB, PRKCA, CUX1, ARRB2, ARRB1, ARF1, ADORA2A, ARF3, SFN, Protein Size: 400
Gene ID
9266
NCBI Accession
NM_017457 , NP_059431
UniProt
Q99418
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