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PYDC1 antibody (N-Term)
PYDC1
Reactivity: Human, Saccharomyces cerevisiae, Guinea Pig, Horse, Cow, Dog, Goat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PYDC1 Antibody
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Target
See all PYDC1 Antibodies
PYDC1
(PYD (Pyrin Domain) Containing 1 (PYDC1))
Binding Specificity
All epitopes for PYDC1 antibodies
N-Term
Reactivity
Human, Saccharomyces cerevisiae, Guinea Pig, Horse, Cow, Dog, Goat
Host
All hosts for PYDC1 antibodies
Rabbit
Clonality
All clonalities for PYDC1 antibodies
Polyclonal
Conjugate
All conjugates for PYDC1 antibodies
This PYDC1 antibody is un-conjugated
Application
All applications for PYDC1 antibodies
Western Blotting (WB)
Sequence
REAILKVLEN LTPEELKKFK MKLGTVPLRE GFERIPRGAL GQLDIVDLTD
Predicted Reactivity
Cow: 83%, Dog: 83%, Goat: 83%, Guinea Pig: 85%, Horse: 83%, Human: 100%, Yeast: 77%
Characteristics
This is a rabbit polyclonal antibody against PYDC1. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human PYDC1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for PYDC1
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Target
PYDC1
(PYD (Pyrin Domain) Containing 1 (PYDC1))
Alternative Name
PYDC1 (PYDC1 Products )
Synonyms
ASC2 antibody, POP1 antibody, PYC1 antibody, pyrin domain containing 1 antibody, PYDC1 antibody
Background
PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro- caspase-1 activation. It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS. Alias Symbols: PYDC1, ASC2, ASCI, POP1, PYC1, Protein Interaction Partner: WDR82, Protein Size: 89
Gene ID
260434
NCBI Accession
NP_690865
UniProt
Q8WXC3
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