VAMP1 antibody
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- Target See all VAMP1 Antibodies
- VAMP1 (Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1))
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Reactivity
- Human, Rat, Mouse, Rabbit, Cow, Pig, Hamster
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This VAMP1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- The antibody is specific for the ~16 kDa synaptobrevin protein in Western blots of rat brain lysate.
- Cross-Reactivity (Details)
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Species reactivity (tested):Human, Pig, Hamster, Rat, Rabbit, Mouse, and Bovine.
Also reacts to: VAMP2 - Purification
- Affinity Chromatography.
- Immunogen
- Synaptic immunoprecipitate (crude) from Human brain.
- Clone
- SP10
- Isotype
- IgM
- Top Product
- Discover our top product VAMP1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store the antibody undiluted (in aliquots) at -20 °C.
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- Target
- VAMP1 (Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1))
- Alternative Name
- VAMP-1 / Synaptobrevin-1 (VAMP1 Products)
- Synonyms
- SYB1 antibody, VAMP-1 antibody, Syb1 antibody, zgc:73378 antibody, wu:fj59a03 antibody, Syb-1 antibody, lew antibody, VAMP1 antibody, syb1 antibody, vamp-1 antibody, An12g07570 antibody, vesicle associated membrane protein 1 antibody, vesicle-associated membrane protein 1 antibody, vesicle-associated membrane protein 1 (synaptobrevin 1) antibody, vesicle associated membrane protein 1 L homeolog antibody, synaptobrevin 1 antibody, zgc:92912 antibody, VAMP1 antibody, Vamp1 antibody, vamp1 antibody, vamp1.L antibody, LOC100224955 antibody, ANI_1_906104 antibody, zgc:92912 antibody
- Background
- Synaptobrevin (aka VAMP) is an integral membrane protein of synaptic vesicles that plays a major role in the formation of larger SNARE complexes, along with SNAP-25 and syntaxin. Synaptobrevin has been shown to be essential for two fast synapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter release and fast endocytosis that mediates rapid recycling of synaptic vesicles (Deak et al., 2004). Decreased levels of synaptobrevin in human hippocampus and cortex have been correlated with cognitive defects in Alzheimer's disease (Sze et al., 2000).Synonyms: SYB1, VAMP1, Vesicle-associated membrane protein 1
- Gene ID
- 6843
- NCBI Accession
- NP_055046
- UniProt
- P23763
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