APOB
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Peptide ELISA: 1/32000. Western Blot: 0.3 - 1 μg/mL, Bands corresponding to the exopected sizes of ApoB100 andApoB48 were detected in Human serum samples from five different individuals. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Apolipoprotein B consists of a single polypeptide chain with a molecular weight of 516 kDa and is mostly synthesised in the liver. It is a major apolipoprotein of very low density, intermediate density and low density lipoproteins (LDL) as well as being a major component of lipoprotein (a). Apolipoprotein B is a ligand for the LDL receptor and elevated levels are associated with premature atherosclerosis. Normal plasma apolipoprotein B levels are around 800 mg/L.Synonyms: Apo-B, ApoB, ApoB-100, ApoB100