CALHM1 antibody (Calcium Homeostasis Modulator 1) (N-Term)

Details for Product anti-CALHM1 Antibody No. ABIN5554639, Supplier: Log in to see
Antigen
  • FAM26C
  • Fam26c
  • RGD1564891
  • EG546729
  • calcium homeostasis modulator 1
  • novel protein similar to vertebrate calcium homeostasis modulator protein family
  • CALHM1
  • LOC557535
  • LOC100349950
  • Calhm1
Epitope
N-Term
6
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
38
27
24
1
1
1
1
1
1
Host
Rabbit
38
Clonality
Polyclonal
Conjugate
This CALHM1 antibody is un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
23
14
13
10
6
3
Options
Supplier
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Immunogen 17 amino acid peptide near the amino terminus of Human CALHM1
Isotype IgG
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse, Rat.
Purification Affinity chromatography purified via peptide column
Alternative Name CALHM1 / FAM26C (CALHM1 Antibody Abstract)
Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by a massive loss of neurons in several brain regions and by the presence of senile plaques comprised of aggregated amyloid-b (Ab) peptides produced by the endoproteolysis of the amyloid precursor protein (APP). The calcium homeostasis modulator 1 (CALHM1) is a recently identified multipass transmembrane glycoprotein that controls cytosolic Ca2+ concentration and Ab levels. While some studies suggest CALHM1 is significantly associated with risk of AD, other reports suggest there is no link. CALHM1 has been suggested to modulate the Ca2+-dependent proteolytic process of APP through controlling the level of cytosolic Ca2+.Synonyms: Calcium homeostasis modulator protein 1
Gene ID 255022
NCBI Accession NP_001001412
UniProt Q8IU99
Application Notes ELISA. Western Blot: CALHM1 antibody can be used for detection of CALHM1 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS containing 0.02 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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