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TIMD4 antibody (Center)

TIMD4 Reactivity: Human, Mouse WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500917
  • Target See all TIMD4 Antibodies
    TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))
    Binding Specificity
    • 13
    • 9
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 34
    • 16
    • 5
    • 2
    • 1
    Human, Mouse
    Host
    • 31
    • 6
    • 3
    • 2
    • 1
    Rabbit
    Clonality
    • 30
    • 12
    • 1
    Polyclonal
    Conjugate
    • 27
    • 4
    • 3
    • 3
    • 3
    • 3
    This TIMD4 antibody is un-conjugated
    Application
    • 30
    • 26
    • 11
    • 10
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects TIMD4 at center.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Mouse.
    Purification
    Peptide affinity chromatography
    Immunogen
    TIM-4 antibody was raised against a 16 amino acid peptide from near the center of human TIM-4.
    Isotype
    IgG
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  • Application Notes
    ELISA. Western blot: 1 - 2 μg/mL. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS, 0.02 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))
    Alternative Name
    TIMD4 (TIMD4 Products)
    Synonyms
    RGD1564516 antibody, MGC99322 antibody, TIMD4 antibody, B430010N18Rik antibody, TIM-4 antibody, Tim4 antibody, SMUCKLER antibody, TIM4 antibody, T-cell immunoglobulin and mucin domain containing 4 antibody, T-cell immunoglobulin and mucin domain containing 4 L homeolog antibody, T cell immunoglobulin and mucin domain containing 4 antibody, Timd4 antibody, TIMD4 antibody, timd4.L antibody
    Background
    The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.Synonyms: T-cell immunoglobulin and mucin domain-containing protein 4, T-cell membrane protein 4, TIM-4, TIM4, TIMD-4
    Gene ID
    91937
    NCBI Accession
    NP_612388
    Pathways
    Cancer Immune Checkpoints
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