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HSPBP1 antibody (N-Term)
HSPBP1
Reactivity: Human
WB, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HSPBP1 Antibody
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Target
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HSPBP1
(HSPA Binding Protein, Cytoplasmic Cochaperone 1 (HSPBP1))
Binding Specificity
All epitopes for HSPBP1 antibodies
AA 68-97, N-Term
Reactivity
All reactivities for HSPBP1 antibodies
Human
Host
All hosts for HSPBP1 antibodies
Rabbit
Clonality
All clonalities for HSPBP1 antibodies
Polyclonal
Conjugate
All conjugates for HSPBP1 antibodies
This HSPBP1 antibody is un-conjugated
Application
All applications for HSPBP1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human HSPBP1 (N-term).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 68-97 amino acids from the N-terminal region of human HSPBP1
Isotype
Ig Fraction
Top Product
Discover our top product HSPBP1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for HSPBP1
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Target
HSPBP1
(HSPA Binding Protein, Cytoplasmic Cochaperone 1 (HSPBP1))
Alternative Name
HSPBP1 (HSPBP1 Products )
Synonyms
FES1 antibody, 1500019G21Rik antibody, HSPA (Hsp70) binding protein 1 antibody, HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 antibody, HSPBP1 antibody, Hspbp1 antibody
Background
HSPBP1 inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.Synonyms: HSPBP, Heat shock protein-binding protein 1, Hsp70-binding protein 1, Hsp70-binding protein 2, Hsp70-interacting protein 1, Hsp70-interacting protein 2, HspBP2
Molecular Weight
39474 Da
Gene ID
23640
NCBI Accession
NP_001123578
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