PANX1 antibody (N-Term)
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- Target See all PANX1 Antibodies
- PANX1 (Pannexin 1 (PANX1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PANX1 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1.
- Isotype
- IgG
- Top Product
- Discover our top product PANX1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % Sodium Azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store the antibody (in aliquots) at -20 °C.
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- Target
- PANX1 (Pannexin 1 (PANX1))
- Alternative Name
- PANX1 (PANX1 Products)
- Synonyms
- panx1 antibody, zgc:55631 antibody, PANX1 antibody, px1 antibody, mrs1 antibody, pannexin1 antibody, Pannexin-1 antibody, MRS1 antibody, PX1 antibody, UNQ2529 antibody, AI847747 antibody, pannexin 1a antibody, pannexin 1 antibody, Pannexin 1 antibody, panx1a antibody, PANX1 antibody, panx1 antibody, Panx1 antibody
- Background
- The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.Synonyms: MRS1, PX1, Pannexin 1, Pannexin-1, UNQ2529
- Molecular Weight
- 47 kDa
- Gene ID
- 24145
- NCBI Accession
- NP_056183
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