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PARP1 antibody (Poly (ADP-Ribose) Polymerase 1) (AA 1-100)

Details for Product anti-PARP1 Antibody No. ABIN559798, Supplier: Log in to see
Antigen
  • 5830444G22Rik
  • Adprp
  • Adprt
  • ADPRT
  • ADPRT1
  • Adprt1
  • adprt1
  • ADPRT 1
  • AI893648
  • ARTD1
  • BEST:LD21673
  • C80510
  • CG17685
  • CG17696
  • CG17718
  • CG40411
  • D.PARP
  • Dm.pARTa
  • Dmel\\CG40411
  • dPARP
  • LD21673.3prime
  • padprt-1
  • pADPRT-1
  • parp
  • PARP
  • Parp-1
  • parp-1
  • PARP-1
  • PARP1
  • PPOL
  • ppol
  • sPARP-1
Alternatives
anti-Human PARP1 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
AA 1-100, partial
67
20
20
20
20
20
20
20
19
19
17
16
16
15
14
12
12
8
6
6
6
6
6
6
6
6
6
6
5
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
377
59
57
11
4
4
4
3
3
1
1
1
1
1
Host
Mouse
383
42
1
Clonality (Clone)
Monoclonal ()
Conjugate
This PARP1 antibody is un-conjugated
25
25
24
24
24
23
1
1
Application
Immunofluorescence (IF), ELISA, Western Blotting (WB)
226
212
173
43
43
35
31
21
12
12
9
4
4
3
2
1
1
1
Supplier
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Available images

Immunogen PARP1 (AAH37545, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: MAESSDKLYR VEYAKSGRAS CKKCSESIPK DSLRMAIMVQ SPMFDGKVPH WYHFSCFWKV GHSIRHPDVE VDGFSELRWD DQQKVKKTAE AGGVTGKGQD
Clone 3G4
Isotype IgG2a kappa
Cross-Reactivity Human
Alternative Name PARP1 (PARP1 Antibody Abstract)
Background Full Gene Name: poly (ADP-ribose) polymerase 1
Synonyms: ADPRT,ADPRT1,PARP,PARP-1,PPOL,pADPRT-1
Gene ID 142
Pathways Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
Immunofluorescence (IF) image for anti-PARP1 antibody (Poly (ADP-Ribose) Polymerase 1) (AA 1-100) (ABIN559798) Immunofluorescence of monoclonal antibody to PARP1 on HeLa cell. [antibody concentrat...
Western Blotting (WB) image for anti-PARP1 antibody (Poly (ADP-Ribose) Polymerase 1) (AA 1-100) (ABIN559798) PARP1 monoclonal antibody (M01), clone 3G4 Western Blot analysis of PARP1 expression ...
ELISA image for anti-PARP1 antibody (Poly (ADP-Ribose) Polymerase 1) (AA 1-100) (ABIN559798) Detection limit for recombinant GST tagged PARP1 is approximately 0.1ng/ml as a captu...
 image for anti-PARP1 antibody (Poly (ADP-Ribose) Polymerase 1) (AA 1-100) (ABIN559798) Western Blot detection against Immunogen (36.63 KDa) .
Immunofluorescence (IF) image for anti-PARP1 antibody (Poly (ADP-Ribose) Polymerase 1) (AA 1-100) (ABIN559798) Immunofluorescence of monoclonal antibody to PARP1 on HeLa cell. (antibody concentrat...
Product cited in: Faraoni, Compagnone, Lavorgna, Angelini, Cencioni, Piras, Panetta, Ottone, Dolci, Venditti, Graziani, Lo-Coco: "BRCA1, PARP1 and ?H2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib." in: Biochimica et biophysica acta, Vol. 1852, Issue 3, pp. 462-72, 2015 (PubMed).

Nicolae, Aho, Vlahos, Choe, De, Karras, Moldovan: "The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13627-37, 2014 (PubMed).

Shen, Oswald, Phelps, Cam, Pelloski, Pang, Houghton: "Regulation of FANCD2 by the mTOR pathway contributes to the resistance of cancer cells to DNA double-strand breaks." in: Cancer research, Vol. 73, Issue 11, pp. 3393-401, 2013 (PubMed).

Luijsterburg, Lindh, Acs, Vrouwe, Pines, van Attikum, Mullenders, Dantuma: "DDB2 promotes chromatin decondensation at UV-induced DNA damage." in: The Journal of cell biology, Vol. 197, Issue 2, pp. 267-81, 2012 (PubMed).

Pines, Vrouwe, Marteijn, Typas, Luijsterburg, Cansoy, Hensbergen, Deelder, de Groot, Matsumoto, Sugasawa, Thoma, Vermeulen, Vrieling, Mullenders: "PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1." in: The Journal of cell biology, Vol. 199, Issue 2, pp. 235-49, 2012 (PubMed).

Crawford, Yang, Mattaini, Hunter: "The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor." in: The Journal of biological chemistry, Vol. 284, Issue 42, pp. 28660-73, 2009 (PubMed).