PARP1 antibody (Poly (ADP-Ribose) Polymerase 1) (AA 1-100)

Details for Product anti-PARP1 Antibody No. ABIN559798, Supplier: Log in to see
Antigen
  • BEST:LD21673
  • CG17685
  • CG17696
  • CG17718
  • CG40411
  • D.PARP
  • Dm.pARTa
  • Dmel\\CG40411
  • LD21673.3prime
  • PARP
  • PARP-1
  • PARP1
  • dPARP
  • parp
  • ADPRT
  • ADPRT 1
  • ADPRT1
  • ARTD1
  • PPOL
  • pADPRT-1
  • Adprt
  • Parp-1
  • adprt1
  • padprt-1
  • ppol
  • 5830444G22Rik
  • AI893648
  • Adprp
  • Adprt1
  • C80510
  • parp-1
  • sPARP-1
  • Poly-(ADP-ribose) polymerase
  • poly (ADP-ribose) polymerase 1
  • poly (ADP-ribose) polymerase family, member 1
  • poly ADP-ribose polymerase
  • Parp
  • PARP1
  • Parp1
  • parp1
Alternatives
anti-Human PARP1 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
AA 1-100, partial
58
19
19
19
19
19
19
19
18
18
18
17
15
14
12
9
8
8
8
6
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4
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
385
84
80
18
17
13
9
9
7
6
5
3
2
2
1
1
1
1
1
Host
Mouse
378
45
1
Clonality (Clone)
Monoclonal ()
Conjugate
This PARP1 antibody is un-conjugated
25
24
24
24
24
23
Application
Immunofluorescence (IF), ELISA, Western Blotting (WB)
236
231
164
50
44
41
31
21
13
12
6
4
4
4
2
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen PARP1 (AAH37545, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: MAESSDKLYR VEYAKSGRAS CKKCSESIPK DSLRMAIMVQ SPMFDGKVPH WYHFSCFWKV GHSIRHPDVE VDGFSELRWD DQQKVKKTAE AGGVTGKGQD
Clone 3G4
Isotype IgG2a kappa
Cross-Reactivity Human
Alternative Name PARP1 (PARP1 Antibody Abstract)
Background Full Gene Name: poly (ADP-ribose) polymerase 1
Synonyms: ADPRT,ADPRT1,PARP,PARP-1,PPOL,pADPRT-1
Gene ID 142
Pathways Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
Immunofluorescence (IF) image for anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100), (partial) antibody (ABIN559798) Immunofluorescence of monoclonal antibody to PARP1 on HeLa cell. [antibody concentrat...
Western Blotting (WB) image for anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100), (partial) antibody (ABIN559798) PARP1 monoclonal antibody (M01), clone 3G4 Western Blot analysis of PARP1 expression ...
ELISA image for anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100), (partial) antibody (ABIN559798) Detection limit for recombinant GST tagged PARP1 is approximately 0.1ng/ml as a captu...
 image for anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100), (partial) antibody (ABIN559798) Western Blot detection against Immunogen (36.63 KDa) .
Immunofluorescence (IF) image for anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100), (partial) antibody (ABIN559798) Immunofluorescence of monoclonal antibody to PARP1 on HeLa cell. (antibody concentrat...
Product cited in: Faraoni, Compagnone, Lavorgna, Angelini, Cencioni, Piras, Panetta, Ottone, Dolci, Venditti, Graziani, Lo-Coco: "BRCA1, PARP1 and ?H2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib." in: Biochimica et biophysica acta, Vol. 1852, Issue 3, pp. 462-72, 2015 (PubMed).

Nicolae, Aho, Vlahos, Choe, De, Karras, Moldovan: "The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13627-37, 2014 (PubMed).

Shen, Oswald, Phelps, Cam, Pelloski, Pang, Houghton: "Regulation of FANCD2 by the mTOR pathway contributes to the resistance of cancer cells to DNA double-strand breaks." in: Cancer research, Vol. 73, Issue 11, pp. 3393-401, 2013 (PubMed).

Luijsterburg, Lindh, Acs, Vrouwe, Pines, van Attikum, Mullenders, Dantuma: "DDB2 promotes chromatin decondensation at UV-induced DNA damage." in: The Journal of cell biology, Vol. 197, Issue 2, pp. 267-81, 2012 (PubMed).

Pines, Vrouwe, Marteijn, Typas, Luijsterburg, Cansoy, Hensbergen, Deelder, de Groot, Matsumoto, Sugasawa, Thoma, Vermeulen, Vrieling, Mullenders: "PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1." in: The Journal of cell biology, Vol. 199, Issue 2, pp. 235-49, 2012 (PubMed).

Crawford, Yang, Mattaini, Hunter: "The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor." in: The Journal of biological chemistry, Vol. 284, Issue 42, pp. 28660-73, 2009 (PubMed).

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