IRF1 antibody (Interferon Regulatory Factor 1) (AA 216-325)

Details for Product anti-IRF1 Antibody No. ABIN561520, Supplier: Log in to see
Antigen
  • irf1
  • zgc:136945
  • IRF1
  • irf11
  • zgc:103566
  • IRF-1
  • MAR
  • AU020929
  • Irf-1
  • interferon regulatory factor 1
  • interferon regulatory factor 1a
  • interferon regulatory factor 1b
  • IRF1
  • irf1a
  • irf1b
  • Irf1
Alternatives
anti-Human IRF1 antibody for Dot Blot
Epitope
AA 216-325, partial
16
15
15
14
11
8
8
6
6
5
5
5
5
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
111
47
21
11
11
11
9
9
8
6
5
1
1
1
Host
Mouse
106
28
2
1
Clonality (Clone)
Monoclonal ()
Conjugate
This IRF1 antibody is un-conjugated
7
7
6
5
5
5
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
122
56
12
12
10
7
6
4
3
2
1
1
1
Options
Supplier
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Available images

Immunogen IRF1 (NP_002189, 216 a.a. ~ 325 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: PMPSTSEATT DEDEEGKLPE DIMKLLEQSE WQPTNVDGKG YLLNEPGVQP TSVYGDFSCK EEPEIDSPGG DIGLSLQRVF TDLKNMDATW LDSLLTPVRL PSIQAIPCAP
Clone 2E4
Isotype IgG2a kappa
Cross-Reactivity Human
Alternative Name IRF1 (IRF1 Antibody Abstract)
Background Full Gene Name: interferon regulatory factor 1
Synonyms: IRF-1,MAR
Gene ID 3659
NCBI Accession NP_002189, NM_002198
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Pathways Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
Western Blotting (WB) image for anti-IRF1 antibody (Interferon Regulatory Factor 1) (AA 216-325) (ABIN561520) IRF1 monoclonal antibody (M01), clone 2E4 Western Blot analysis of IRF1 expression in...
ELISA image for anti-IRF1 antibody (Interferon Regulatory Factor 1) (AA 216-325) (ABIN561520) Detection limit for recombinant GST tagged IRF1 is approximately 0.1ng/ml as a captur...
 image for anti-IRF1 antibody (Interferon Regulatory Factor 1) (AA 216-325) (ABIN561520) Western Blot detection against Immunogen (37.84 KDa) .
Product cited in: Bartlett, Slater, Glanville, Haas, Caramori, Casolari, Clarke, Message, Aniscenko, Kebadze, Zhu, Mallia, Mizgerd, Belvisi, Papi, Kotenko, Johnston, Edwards: "Defining critical roles for NF-?B p65 and type I interferon in innate immunity to rhinovirus." in: EMBO molecular medicine, Vol. 4, Issue 12, pp. 1244-60, 2012 (PubMed).

Baumjohann, Okada, Ansel: "Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 5, pp. 2089-92, 2011 (PubMed).

Choi, Kageyama, Eto, Escobar, Johnston, Monticelli, Lao, Crotty: "ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6." in: Immunity, Vol. 34, Issue 6, pp. 932-46, 2011 (PubMed).

Fazilleau, McHeyzer-Williams, Rosen, McHeyzer-Williams: "The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding." in: Nature immunology, Vol. 10, Issue 4, pp. 375-84, 2009 (PubMed).

Nurieva, Chung, Martinez, Yang, Tanaka, Matskevitch, Wang, Dong: "Bcl6 mediates the development of T follicular helper cells." in: Science (New York, N.Y.), Vol. 325, Issue 5943, pp. 1001-5, 2009 (PubMed).

Steffen, MacKay, Kerr, Tsuchiya, Hu, Fox, Dang, Johnston, Oakes, Tchao, Pak, Fields, Kennedy, Kaeberlein: "Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4." in: Cell, Vol. 133, Issue 2, pp. 292-302, 2008 (PubMed).

Ye, Lista, Lo Coco, Knowles, Offit, Chaganti, Dalla-Favera: "Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma." in: Science (New York, N.Y.), Vol. 262, Issue 5134, pp. 747-50, 1993 (PubMed).