LUM antibody (Middle Region)
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- Target See all LUM Antibodies
- LUM (Lumican (LUM))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LUM antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- AFKGLKSLEY LDLSFNQIAR LPSGLPVSLL TLYLDNNKIS NIPDEYFKRF
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against LUM. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human LUM
- Top Product
- Discover our top product LUM Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 338 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- LUM (Lumican (LUM))
- Alternative Name
- LUM (LUM Products)
- Synonyms
- MGC64527 antibody, zgc:86661 antibody, ldc antibody, slrr2d antibody, DKFZp468L1116 antibody, LDC antibody, SLRR2D antibody, Ldc antibody, lumican antibody, lumican L homeolog antibody, LUM antibody, lum.L antibody, lum antibody, CpipJ_CPIJ010209 antibody, Lum antibody
- Background
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This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.
Alias Symbols: LDC, SLRR2D
Protein Interaction Partner: GNAQ, TRA2B, MMP14, ACAN, COL1A2,
Protein Size: 338 - Molecular Weight
- 37 kDa
- Gene ID
- 4060
- NCBI Accession
- NM_002345, NP_002336
- UniProt
- P51884
- Pathways
- Glycosaminoglycan Metabolic Process
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