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LUM Products

(Lumican (LUM))

Categories

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008].

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Featured LUM Categories

LUM Antibodies

High quality antibodies with extensive validation data.

LUM ELISA Kits

Reliable ELISA kits for a wide range of species.

LUM Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LUM Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN391881
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7433708
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN391882
Quantity 400 μL
Datasheet Datasheet

Recommended LUM ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6957545
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6973974
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968359
Quantity 96 tests
Datasheet Datasheet

Recommended LUM Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
Cat. No. ABIN1309888
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320810
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123797
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our LUM products

Barbariga, Vallone, Mosca, Bignami, Magagnotti, Fonteyne, Chiappori, Milanesi, Rama, Andolfo, Ferrari: "The role of extracellular matrix in mouse and human corneal neovascularization." in: Scientific reports, Vol. 9, Issue 1, pp. 14272, (2019) (PubMed).

Zhao, Li, Xu, He, Cui, Lv: "Lumican alleviates hypertrophic scarring by suppressing integrin-FAK signaling." in: Biochemical and biophysical research communications, Vol. 480, Issue 2, pp. 153-159, (2016) (PubMed).

Gu, Wan, Xue, Cheng, Zheng, Zhao, Fan, Han, Tong, Yao: "Lumican as a novel potential clinical indicator for acute aortic dissection: A comparative study, based on multi-slice computed tomography angiography." in: Experimental and therapeutic medicine, Vol. 11, Issue 3, pp. 923-928, (2016) (PubMed).

Cappellesso, Millioni, Arrigoni, Simonato, Caroccia, Iori, Guzzardo, Ventura, Tessari, Fassina: "Lumican is overexpressed in lung adenocarcinoma pleural effusions." in: PLoS ONE, Vol. 10, Issue 5, pp. e0126458, (2015) (PubMed).

Gasimli, Hickey, Yang, Li, dela Rosa, Nairn, Kulik, Dordick, Moremen, Dalton, Linhardt: "Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages." in: Biochimica et biophysica acta, Vol. 1840, Issue 6, pp. 1993-2003, (2014) (PubMed).

Gasimli, Stansfield, Nairn, Liu, Paluh, Yang, Dordick, Moremen, Linhardt: "Structural remodeling of proteoglycans upon retinoic acid-induced differentiation of NCCIT cells." in: Glycoconjugate journal, Vol. 30, Issue 5, pp. 497-510, (2013) (PubMed).

Barderas, Mendes, Torres, Bartolomé, López-Lucendo, Villar-Vázquez, Peláez-García, Fuente, Bonilla, Casal: "In-depth characterization of the secretome of colorectal cancer metastatic cells identifies key proteins in cell adhesion, migration, and invasion." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 6, pp. 1602-20, (2013) (PubMed).

de Wit, Belt, Delis-van Diemen, Carvalho, Coupé, Stockmann, Bril, Beliën, Fijneman, Meijer: "Lumican and versican are associated with good outcome in stage II and III colon cancer." in: Annals of surgical oncology, Vol. 20 Suppl 3, pp. S348-59, (2013) (PubMed).

Xia, Hong, Ye, Wang, Chen, Liu: "Label-free quantitative proteomic analysis of right ventricular remodeling in infant Tetralogy of Fallot patients." in: Journal of proteomics, Vol. 84, pp. 78-91, (2013) (PubMed).

Gu, Cheng, Yao, Yin, Tong, Rao, Yen, Ku, Rao: "Quantitative proteomics analysis by isobaric tags for relative and absolute quantitation identified Lumican as a potential marker for acute aortic dissection." in: Journal of biomedicine & biotechnology, Vol. 2011, pp. 920763, (2012) (PubMed).

Synonyms and alternative names related to LUM

lumican (LUM), lumican L homeolog (lum.L), lumican (lum), lumican (CpipJ_CPIJ010209), lumican (Lum), DKFZp468L1116, ldc, LDC, Ldc, MGC64527, slrr2d, SLRR2D, zgc:86661

Protein level used designations for LUM

  • lumican
  • zlum
  • Keratan sulfate proteoglycan lumican
  • KSPG lumican
  • keratan sulfate proteoglycan lumican
  • lumican proteoglycan
  • KSPG
  • corneal keratan sulfate proteoglycan 37B core protein
  • keratan sulfate proteoglycan
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