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SFRP1 antibody (C-Term)
SFRP1
Reactivity: Human, Mouse, Cow
IHC (p), EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-SFRP1 Antibody
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Target
See all SFRP1 Antibodies
SFRP1
(Secreted Frizzled-Related Protein 1 (SFRP1))
Binding Specificity
All epitopes for SFRP1 antibodies
C-Term
Reactivity
All reactivities for SFRP1 antibodies
Human, Mouse, Cow
Host
All hosts for SFRP1 antibodies
Goat
Clonality
All clonalities for SFRP1 antibodies
Polyclonal
Conjugate
All conjugates for SFRP1 antibodies
This SFRP1 antibody is un-conjugated
Application
All applications for SFRP1 antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Sequence
KNHECPTFQS VFK
Specificity
Recognizes Secreted Frizzled-related Protein 1 (SFRP1) at C-term.
Cross-Reactivity (Details)
Species reactivity (expected):Bovine and Mouse. Species reactivity (tested):Human.
Purification
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Immunogen
Synthetic peptide corresponding to the C-terminus of Human SFRP1 (NP_003003.3).
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for SFRP1
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Target
SFRP1
(Secreted Frizzled-Related Protein 1 (SFRP1))
Alternative Name
SFRP1 (SFRP1 Products )
Synonyms
FRP antibody, FRP-1 antibody, FRP1 antibody, FrzA antibody, SARP2 antibody, 2210415K03Rik antibody, AW011917 antibody, AW107218 antibody, AW742929 antibody, sFRP-1 antibody, CSFRP1 antibody, SFRP1 antibody, XfrzA antibody, frp antibody, frp-1 antibody, frp1 antibody, frzA antibody, sarp2 antibody, sfrp1 antibody, LOC100231868 antibody, Srfp1a antibody, wu:fd19b09 antibody, secreted frizzled related protein 1 antibody, secreted frizzled-related protein 1 antibody, Secreted frizzled-related protein 1 antibody, secreted frizzled-related protein 1a antibody, secreted frizzled-related protein 1b antibody, SFRP1 antibody, Sfrp1 antibody, sfrp1 antibody, sfrp1a antibody, sfrp1b antibody
Background
SFRP1 (also known as FRP, FRP1, SARP2, Secreted Apoptosis-related Protein 2, Secreted Frizzled-related Protein and Secreted frizzled-related protein 1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 and SFRP5 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP1 is expressed in several human tissues, with the highest levels in heart.Synonyms: FRP, FRP-1, FRP1, SARP-2, SARP2, SFRP-1, Secreted apoptosis-related protein 2, Secreted frizzled-related protein 1
Gene ID
6422
NCBI Accession
NP_003003
UniProt
Q8N474
Pathways
WNT Signaling , Intracellular Steroid Hormone Receptor Signaling Pathway , Negative Regulation of Hormone Secretion , Regulation of Intracellular Steroid Hormone Receptor Signaling , Stem Cell Maintenance , Tube Formation , Positive Regulation of fat Cell Differentiation
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