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SCD antibody (C-Term)
SCD
Reactivity: Human
IHC (p), EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-SCD Antibody
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Target
See all SCD Antibodies
SCD
(Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))
Binding Specificity
All epitopes for SCD antibodies
C-Term
Reactivity
All reactivities for SCD antibodies
Human
Host
All hosts for SCD antibodies
Goat
Clonality
All clonalities for SCD antibodies
Polyclonal
Conjugate
All conjugates for SCD antibodies
This SCD antibody is un-conjugated
Application
All applications for SCD antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
Recognizes Stearoyl-CoA desaturase.
Purification
Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
Immunogen
Peptide with sequence C-RIKRTGDGNYKSG, from the C Terminus of the protein sequence according to NP_005054.3.
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for SCD
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Target
SCD
(Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))
Alternative Name
SCD / SCD1 (SCD Products )
Synonyms
FADS5 antibody, MSTP008 antibody, SCD1 antibody, SCDOS antibody, AA589638 antibody, AI265570 antibody, Scd antibody, Scd-1 antibody, ab antibody, SCD antibody, fads5 antibody, scd1 antibody, scdos antibody, F27J15.17 antibody, F27J15_17 antibody, STOMATAL CYTOKINESIS-DEFECTIVE 1 antibody, cds2 antibody, desaturase antibody, stearoyl-CoA desaturase antibody, acyl-CoA desaturase antibody, Acyl-CoA desaturase antibody, stearoyl-Coenzyme A desaturase 1 antibody, stearoyl-CoA desaturase (delta-9-desaturase) antibody, stearoyl-CoA desaturase (delta-9-desaturase) S homeolog antibody, stomatal cytokinesis defective / SCD1 protein (SCD1) antibody, acyl-CoA desaturase-like antibody, SCD antibody, CIMG_08158 antibody, VIBHAR_RS23280 antibody, acod antibody, Scd1 antibody, Scd antibody, scd antibody, LOC100346561 antibody, scd.S antibody, SCD1 antibody, LOC100719661 antibody, LOC101835884 antibody, LOC109101093 antibody
Background
Stearoyl-CoA desaturase (SCD, EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5 (MIM 608370), have been identified in human. SCD1 shares about 85 % amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Zhang et al. (1999) [PubMed 10229681], Wang et al., 2005).Synonyms: Acyl-CoA desaturase, Delta(9)-desaturase, Fatty acid desaturase, Stearoyl-CoA desaturase
Gene ID
6319
NCBI Accession
NP_005054
UniProt
O00767
Pathways
Brown Fat Cell Differentiation
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