AIM2 antibody (C-Term)

Catalog No. ABIN569662

This Goat Polyclonal antibody specifically detects AIM2 in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for AIM2 antibody (C-Term) (ABIN569662)

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This AIM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-AIM2 Antibody

Binding Specificity: C-Term

Sequence: C-GEKLQLTSGV HSTIK

Specificity: This antibody detects AIM2 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the C-Terminus of the protein sequence according to NP_004824.1. Genename: AIM2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for AIM2

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Alternative Name: AIM2

Background: AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon gamma induces expression of AIM2.Synonyms: Absent in melanoma 2, Interferon-inducible protein AIM2

Gene ID: 9447

NCBI Accession: NP_004824

UniProt: O14862

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome