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AIM2 antibody (Absent in Melanoma 2) (AA 1-343) Primary Antibody

AIM2 Reactivity: Human IP, WB Host: Rabbit Polyclonal unconjugated
Pubmed (1)
Catalog No. ABIN948806
$585.71
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days
  • Target
    AIM2
    Binding Specificity
    • 15
    • 12
    • 8
    • 8
    • 8
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-343
    Reactivity
    • 80
    • 24
    • 18
    • 3
    • 3
    • 1
    Human
    Host
    • 61
    • 11
    • 9
    Rabbit
    Clonality
    • 73
    • 8
    Polyclonal
    Conjugate
    • 42
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIM2 antibody is un-conjugated
    Application
    • 64
    • 44
    • 24
    • 23
    • 20
    • 13
    • 13
    • 6
    • 4
    • 3
    • 2
    • 1
    Immunoprecipitation (IP), Western Blotting (WB)
    Purpose
    Rabbit polyclonal antibody raised against a full-length human AIM2 protein.
    Brand
    MaxPab®
    Cross-Reactivity
    Human
    Immunogen

    immunogen: AIM2 (NP_004824.1, 1 a.a. ~ 343 a.a) full-length human protein.

    Immunogen Sequence: MESKYKEILLLTGLDNITDEELDRFKFFLSDEFNIATGKLHTANRIQVATLMIQNAGAVSAVMKTIRIFQKLNYMLLAKRLQEEKEKVDKQYKSVTKPKPLSQAEMSPAASAAIRNDVAKQRAAPKVSPHVKPEQKQMVAQQESIREGFQKRCLPVMVLKAKKPFTFETQEGKQEMFHATVATEKEFFFVKVFNTLLKDKFIPKRIIIIARYYRHSGFLEVNSASRVLDAESDQKVNVPLNIIRKAGETPKINTLQTQPLGTIVNGLFVVQKVTEKKKNILFDLSDNTGKMEVLGVRNEDTMKCKEGDKVRLTFFTLSKNGEKLQLTSGVHSTIKVIKAKKKT

  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Product Quality tested by: Antibody reactive against mammalian transfected lysate.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    No additive
    Preservative
    Without preservative
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Adamczak, de Rivero Vaccari, Dale, Brand, Nonner, Bullock, Dahl, Dietrich, Keane: "Pyroptotic neuronal cell death mediated by the AIM2 inflammasome." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 34, Issue 4, pp. 621-9, 2014 (PubMed).

  • Target
    AIM2
    Alternative Name
    AIM2 (AIM2 Antibody Abstract)
    Synonyms
    AIM2, PYHIN4, Gm1313, Ifi210, absent in melanoma 2, AIM2, Aim2
    Background
    Full Gene Name: absent in melanoma 2
    Synonyms: PYHIN4
    Gene ID
    9447
    NCBI Accession
    NP_004824, NM_004833
    Pathways
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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