Tyrosinase  (TYR) (AA 1-433) antibody

Details for Product No. ABIN573956, Supplier: Log in to see
Antigen
  • sandy
  • zgc:109705
  • TYR
  • TYRO
  • tyr
  • LOC100136546
  • CMM8
  • OCA1A
  • OCAIA
  • SHEP3
  • albino
  • c
  • skc35
  • C
  • tyrosinase
  • hypothetical protein
  • tyrosinase (oculocutaneous albinism IA)
  • tyr
  • tyrosinase
  • TYR
  • Celal_3121
  • Halhy_4121
  • Mesop_2736
  • LOC100136546
  • Tyr
Epitope
AA 1-433
15
9
9
6
6
6
5
5
4
3
3
3
2
2
2
2
1
1
1
Reactivity
Cat (Feline), Dog (Canine), Human
196
39
30
15
10
7
3
2
2
2
2
2
1
1
1
1
1
1
Host
Mouse
113
92
2
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
8
6
5
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
131
82
82
75
54
49
42
28
23
13
4
3
2
1
Options
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Supplier Product No.
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Brand IHC-plus™
Immunogen Recombinant tyrosinase protein. Epitope: 1-433.

Type of Immunogen: Recombinant protein
Clone T311
Isotype IgG2a
Specificity Recognizes a cluster of proteins between 70-80kD, identified as human tyrosinase. Occasionally a minor band at 55kD is also detected. Does not cross-react with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Species cross-reactivity: canine and feline. Weak cross-reactivity with mouse.
Purification Protein A purified
Alternative Name Tyrosinase (TYR Antibody Abstract)
Background Name/Gene ID: TYR

Synonyms: TYR, CMM8, LB24-AB, SHEP3, SK29-AB, Monophenol monooxygenase, Tumor rejection antigen AB, OCA1A, Tyrosinase, OCAIA
Gene ID 7299
UniProt P14679
Research Area Signaling, Metabolism
Application Notes Approved: ELISA, ICC, IF, IHC-P (10 μg/mL), WB (1 - 2 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.
Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer PBS, pH 7.4, 0.2 % BSA, 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C,-20 °C
Storage Comment +4°C or -20°C, Avoid repeated freezing and thawing.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Tyrosinase  (TYR) (AA 1-433) antibody (ABIN573956) Human Skin (formalin-fixed, paraffin-embedded) stained with TYR antibody ABIN573956 a...
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