FCGR2B antibody (AA 298-310)

Catalog No. ABIN574375

Product Details anti-FCGR2B Antibody

Target: FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))

Binding Specificity: AA 298-310

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This FCGR2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human FCGR2B / CD32B. This antibody is expected to recognise all reported isoforms (NP_001002273.1, NP_001002274.1, NP_001002275.1, NP_003992.3, NP_001177757.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-PDALEEPDDQNRI from the C-terminus of human FCGR2B / CD32B (NP_003992.3, NP_001002273.1, NP_001002274.1, NP_001002275.1, NP_001177757.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%), Monkey (92%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:16000), WB (0.3 - 1 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for FCGR2B

Target: FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))

Alternative Name: FCGR2B / CD32B (FCGR2B Products)

Synonyms: CD32 antibody, CD32B antibody, FCG2 antibody, FCGR2 antibody, IGFR2 antibody, FCGR2B antibody, AI528646 antibody, F630109E10Rik antibody, Fc[g]RII antibody, FcgRII antibody, Fcgr2 antibody, Fcgr2a antibody, Fcr-2 antibody, Fcr-3 antibody, Ly-17 antibody, Ly-m20 antibody, LyM-1 antibody, Lym-1 antibody, FCRII antibody, FcRII antibody, Fc fragment of IgG receptor IIb antibody, Fc fragment of IgG, low affinity IIb, receptor (CD32) antibody, Fc receptor, IgG, low affinity IIb antibody, low affinity immunoglobulin gamma Fc region receptor II antibody, FCGR2B antibody, Fcgr2b antibody, LOC100856270 antibody

Background: Name/Gene ID: FCGR2B
Family: Immunoglobulin

Synonyms: FCGR2B, CD32, CD32 antigen, CD32B, CDw32, FCG2, FcRII-b, IgG Fc receptor II-b, Fc gamma RIIb, Fc-gamma RII-b, FCGR2, Fc-gamma-RIIb, IGFR2

Gene ID: 2213

NCBI Accession: NP_003992, NP_001002273, NP_001002274, NP_001002275, NP_001177757

UniProt: P31994

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, BCR Signaling