Cadherin 5 antibody

Catalog No. ABIN600558

Product Details anti-Cadherin 5 Antibody

Target: Cadherin 5 (CDH5)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cadherin 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Neutralization (Neut)

Specificity: Binds to human VE-cadherin.

Purification: Purified

Sterility: Sterile filtered

Immunogen:

Type of Immunogen: Native protein

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo (1:10), Func, IHC, IHC-Fr, IP, Neut, WB (1:10)

Usage: The antibody can be used for immunoassays, Western Blots, Immunoprecipitation and for purification. Furthermore the antibody is useful for Flow Cytometry and for inhibition in biological assays. Immunohistochemistry: 1:10. Useful for staining of frozen sections. Flow Cytometry: 1:10. Western Blot: 1:10. Neutralization: For neutralization of biological activity in vitro dilutions have to be made according to the amounts of VE-cadherin to be inactivated. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a sterile-filtered liquid in PBS, 0.1 % BSA

Handling Advice: Avoid repeated freezing and thawing

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. For long-term storage and to avoid freeze-thaw cycles, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 1 year at -20°C.

Target Details for Cadherin 5

Target: Cadherin 5 (CDH5)

Alternative Name: CD144 / CDH5 / VE Cadherin (CDH5 Products)

Synonyms: 7B4 antibody, AA408225 antibody, Cd144 antibody, VE-Cad antibody, VECD antibody, VEcad antibody, Vec antibody, wu:fc88a07 antibody, CD144 antibody, cadherin-5 antibody, cadherin 5 antibody, CDH5 antibody, Cdh5 antibody, cdh5 antibody

Background: Name/Gene ID: CDH5
Family: Cadherin

Synonyms: CDH5, 7B4, 7B4 antigen, CD144, Cadherin-5, Endothelial-specific cadherin, Vascular endothelial cadherin, VE-cadherin, VEC, CD144 antigen, VE Cadherin

Gene ID: 1003

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2