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Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus) (COCH) (AA 141-190) antibody

Details for Product No. ABIN611208, Supplier: Log in to see
Antigen
  • AW122937
  • Coch-5B2
  • D12H14S564E
  • COCH-5B2
  • COCH5B2
  • DFNA9
  • cochlin
  • coagulation factor C homolog (Limulus polyphemus)
  • coagulation factor C homolog, cochlin (Limulus polyphemus)
  • Coch
  • COCH
Alternatives
anti-Human Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus) antibody for Western Blotting
Epitope
AA 141-190
17
9
9
9
9
8
7
4
3
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Human, Monkey, Mouse (Murine), Rabbit, Rat (Rattus)
58
8
5
1
1
1
1
1
1
1
1
1
Host
Rabbit
55
3
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
4
4
4
Application
Western Blotting (WB)
52
32
18
17
3
2
2
1
Options
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Immunogen Synthetic peptide located between aa141-190 of human COCH (O43405, NP_001128530). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Dog, Bovine, Rabbit, Guinea pig (100%), Elephant, Panda, Horse (92%), Bat, Opossum, Chicken, Platypus, Lizard, Xenopus (85%).

Type of Immunogen: Synthetic peptide
Specificity Human COCH
Predicted Reactivity Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Rabbit, Guinea pig (100%) Horse (92%) Chicken (85%).
Purification Immunoaffinity purified
Alternative Name Cochlin / COCH (COCH Antibody Abstract)
Background Name/Gene ID: COCH

Synonyms: COCH, COCH5B2, COCH-5B2, Cochlin, DFNA9, DFNA31
Gene ID 1690
NCBI Accession NP_001128530
UniProt O43405
Pathways Sensory Perception of Sound
Application Notes Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 0.25 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Distilled water
Concentration Lot specific
Buffer Lyophilized from PBS with 2 % sucrose
Handling Advice Avoid repeat freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Supplier Images
 image for anti-Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus) (COCH) (AA 141-190) antibody (ABIN611208) anti-Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus) (COCH) (AA 141-190) antibody
Product cited in: Anfosso, Bardin, Francès, Vivier, Camoin-Jau, Sampol, Dignat-George: "Activation of human endothelial cells via S-endo-1 antigen (CD146) stimulates the tyrosine phosphorylation of focal adhesion kinase p125(FAK)." in: The Journal of biological chemistry, Vol. 273, Issue 41, pp. 26852-6, 1998 (PubMed).

Jean, Gershenwald, Huang, Luca, Hudson, Tainsky, Bar-Eli: "Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells." in: The Journal of biological chemistry, Vol. 273, Issue 26, pp. 16501-8, 1998 (PubMed).

Xie, Luca, Huang, Gutman, Reich, Johnson, Bar-Eli: "Expression of MCAM/MUC18 by human melanoma cells leads to increased tumor growth and metastasis." in: Cancer research, Vol. 57, Issue 11, pp. 2295-303, 1997 (PubMed).

Lehmann, Riethmüller, Johnson: "MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 24, pp. 9891-5, 1990 (PubMed).