CPT1A antibody (Internal Region)

Catalog No. ABIN614906

The Goat Polyclonal anti-CPT1A antibody is suitable to detect CPT1A in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for CPT1A antibody (Internal Region) (ABIN614906)

Target: CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CPT1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-CPT1A Antibody

Binding Specificity: Internal Region

Sequence: C-DPAQTVEQRL KLFK

Specificity: This antibody detects CPT1A / CPT1-L (Internal).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Immunoaffinity chromatography

Immunogen: Synthetic peptide from an internal region of human CPT1A Genename: CPT1A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for CPT1A

Target: CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))

Alternative Name: CPT1A / CPT1-L

Background: The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.Synonyms: Carnitine O-palmitoyltransferase 1 liver isoform, Carnitine palmitoyltransferase 1A

Gene ID: 1374

NCBI Accession: NP_001027017

UniProt: P50416

Pathways: AMPK Signaling, Regulation of Lipid Metabolism by PPARalpha, Feeding Behaviour, Monocarboxylic Acid Catabolic Process