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LAIR1 antibody (Internal Region)
LAIR1
Reactivity: Human
WB, EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-LAIR1 Antibody
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Target
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LAIR1
(Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
Binding Specificity
All epitopes for LAIR1 antibodies
Internal Region
Reactivity
All reactivities for LAIR1 antibodies
Human
Host
All hosts for LAIR1 antibodies
Goat
Clonality
All clonalities for LAIR1 antibodies
Polyclonal
Conjugate
All conjugates for LAIR1 antibodies
This LAIR1 antibody is un-conjugated
Application
All applications for LAIR1 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Sequence
C-NDTEDVSQAS PSE
Specificity
This antibody is expected to recognize both isoforms (NP_002278.1, NP_068352.1).
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
Immunogen
Peptide with sequence from the internal region of the protein sequence according to NP_002278.1, NP_068352.1. Genename: LAIR1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for LAIR1
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Target
LAIR1
(Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
Alternative Name
CD305 / LAIR1 (LAIR1 Products )
Synonyms
5133400O11Rik antibody, BB115266 antibody, D7Bwg0421e antibody, Lair-1 antibody, mLair-1 antibody, CD305 antibody, LAIR-1 antibody, leukocyte-associated Ig-like receptor 1 antibody, leukocyte associated immunoglobulin like receptor 1 antibody, leukocyte-associated immunoglobulin-like receptor 1 antibody, Lair1 antibody, LAIR1 antibody
Background
LAIR-1 is a 40kD cell surface molecule that functions as an inhibitory receptor on natural killer cells, monocytes and T cells. LAIR-1, otherwise known as CD305, is also expressed by other haematopoeitic cells including B cells, but is not expressed by nonhaematopoietic, platelets or erythrocytes.Synonyms: LAIR-1, Leukocyte-associated immunoglobulin-like receptor 1, hLAIR1
Gene ID
3903
NCBI Accession
NP_002278
UniProt
Q6GTX8
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