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CLCN2 antibody (Internal Region)
CLCN2
Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog
WB, EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-CLCN2 Antibody
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Target
See all CLCN2 Antibodies
CLCN2
(Chloride Channel 2 (CLCN2))
Binding Specificity
All epitopes for CLCN2 antibodies
Internal Region
Reactivity
Human, Mouse, Rat, Rabbit, Cow, Dog
Host
All hosts for CLCN2 antibodies
Goat
Clonality
All clonalities for CLCN2 antibodies
Polyclonal
Conjugate
All conjugates for CLCN2 antibodies
This CLCN2 antibody is un-conjugated
Application
All applications for CLCN2 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Sequence
QQLDEPVNFS DCK
Specificity
This antibody is expected to recognize all reported isoforms (NP_004357.3, NP_001164558.1, NP_001164559.1, NP_001164560.1).
Cross-Reactivity (Details)
Species reactivity (expected):Mouse, Rat, Canine (Dog), Cow, Rabbit . Species reactivity (tested):Human.
Purification
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
Immunogen
Peptide with sequence from the internal region of the protein sequence according to NP_004357.3. Genename: CLCN2
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Discover our top product CLCN2 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for CLCN2
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Target
CLCN2
(Chloride Channel 2 (CLCN2))
Alternative Name
CLCN2 (CLCN2 Products )
Synonyms
CLCN2 antibody, CLC2 antibody, LOC100150892 antibody, AL118368 antibody, ClC-2 antibody, Clc2 antibody, nmf240 antibody, CLC-2 antibody, CIC-2 antibody, ECA2 antibody, ECA3 antibody, EGI11 antibody, EGI3 antibody, EGMA antibody, EJM6 antibody, EJM8 antibody, clC-2 antibody, chloride voltage-gated channel 2 antibody, chloride channel, voltage-sensitive 2a antibody, chloride channel protein 2 antibody, chloride channel, voltage-sensitive 2 antibody, CLCN2 antibody, clcn2a antibody, EHI_142170 antibody, EHI_186860 antibody, Clcn2 antibody
Background
CLCN2 is a voltage-gated chloride channel, a class of proteins that have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This protein is ubiquitously expressed, with moderate expression in aortic and coronary vascular smooth muscle cells and low levels expressed in aortic endothelial cells. Defects in CLCN2 may be the cause of epilepsy with grand mal seizures on awakening, childhood absence epilepsy type 3, and juvenile absence epilepsy. Single nucleotide polymorphisms (SNPs) of CLCN2 may also at as potential modifiers of cystic fibrosis disease severity.Synonyms: CIC-2, CIC2, CLC3, Chloride channel protein 2
Gene ID
1181
NCBI Accession
NP_001164558
UniProt
P51788
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