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MAGED1 antibody (C-Term)
MAGED1
Reactivity: Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MAGED1 Antibody
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Target
See all MAGED1 Antibodies
MAGED1
(Melanoma Antigen Family D, 1 (MAGED1))
Binding Specificity
All epitopes for MAGED1 antibodies
C-Term
Reactivity
All reactivities for MAGED1 antibodies
Mouse, Rat
Host
All hosts for MAGED1 antibodies
Rabbit
Clonality
All clonalities for MAGED1 antibodies
Polyclonal
Conjugate
All conjugates for MAGED1 antibodies
This MAGED1 antibody is un-conjugated
Application
All applications for MAGED1 antibodies
Western Blotting (WB)
Sequence
C-EAEARAEARN RMGIGDE
Specificity
This antibody detects endogenous level of total Melanoma-associated antigen D1 protein.
Cross-Reactivity (Details)
Species reactivity (tested):Mouse, Rat
Purification
Affinity-chromatography using epitope-specific peptide
Immunogen
Peptide with sequence derived from Mouse Melanoma-associated antigen D1.
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Discover our top product MAGED1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store (in aliquots) at -20 °C.
Target Details for MAGED1
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Target
MAGED1
(Melanoma Antigen Family D, 1 (MAGED1))
Alternative Name
MAGE-D1 (MAGED1 Products )
Synonyms
MAGED1 antibody, DLXIN-1 antibody, NRAGE antibody, 2810433C11Rik antibody, 5430405L04Rik antibody, DXBwg1492e antibody, Dlixin antibody, Dlxin-1 antibody, Dlxin1 antibody, MAGE-D1 antibody, mFLJ00163 antibody, Nrage antibody, MAGE family member D1 antibody, melanoma antigen family D, 1 antibody, melanoma antigen, family D, 1 antibody, MAGED1 antibody, Maged1 antibody
Background
Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.Synonyms: MAGE tumor antigen CCF, MAGED1, Melanoma-associated antigen D1, NRAGE, Neurotrophin receptor-interacting MAGE homolog
Molecular Weight
95 kDa
Gene ID
94275
NCBI Accession
NP_062765
UniProt
Q9QYH6
Pathways
Neurotrophin Signaling Pathway
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