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IRAK3 antibody (C-Term)

IRAK3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN633596
  • Target See all IRAK3 Antibodies
    IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
    Binding Specificity
    • 15
    • 10
    • 8
    • 8
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 58
    • 36
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 79
    • 7
    • 1
    Rabbit
    Clonality
    • 73
    • 14
    Polyclonal
    Conjugate
    • 39
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRAK3 antibody is un-conjugated
    Application
    • 72
    • 39
    • 13
    • 13
    • 10
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    IRAK3 antibody was raised against the C terminal of IRAK3
    Purification
    Affinity purified
    Immunogen
    IRAK3 antibody was raised using the C terminal of IRAK3 corresponding to a region with amino acids NTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLL
    Top Product
    Discover our top product IRAK3 Primary Antibody
  • Application Notes
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    IRAK3 Blocking Peptide, catalog no. 33R-6900, is also available for use as a blocking control in assays to test for specificity of this IRAK3 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IRAK3 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
    Alternative Name
    IRAK3 (IRAK3 Products)
    Synonyms
    IRAK3 antibody, si:dkey-150i15.2 antibody, ASRT5 antibody, IRAKM antibody, IrakM antibody, 4833428C18Rik antibody, AI563835 antibody, IRAK-M antibody, interleukin 1 receptor associated kinase 3 antibody, interleukin-1 receptor-associated kinase 3 antibody, IRAK3 antibody, irak3 antibody, Irak3 antibody
    Background
    IRAK3 contains 1 protein kinase domain and 1 death domain and belongs to the Ser/Thr protein kinase family, Pelle subfamily. It inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
    Molecular Weight
    66 kDa (MW of target protein)
    Pathways
    TLR Signaling, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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