NLRC4 antibody (N-Term)

Catalog No. ABIN636272

Product Details anti-NLRC4 Antibody

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRC4 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity chromatography purified

Immunogen: CLAN antibody was raised in rabbit using N terminus sequence MNFIKDNSRA LIQRMGM of the A and B isoforms of the human CLAN protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for NLRC4

Target: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Alternative Name: CLAN (NLRC4 Products)

Synonyms: CARD12 antibody, CLAN antibody, CLAN1 antibody, CLANA antibody, CLANB antibody, CLANC antibody, CLAND antibody, CLR2.1 antibody, IPAF antibody, 9530011P19Rik antibody, Card12 antibody, NLR family CARD domain containing 4 antibody, NLR family, CARD domain containing 4 antibody, NLRC4 antibody, Nlrc4 antibody

Background: A novel human CED-4-like gene, CLAN, is a caspase-associated recruitment domain (CARD)-containing protein and is expressed at varying degrees in normal human tissues. It contributes to a number of intracellular processes including apoptosis, cytokine processing, and NF-kappa B activation.

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome