Insulin Receptor antibody
Quick Overview for Insulin Receptor antibody (ABIN637020)
Target
See all Insulin Receptor (INSR) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Affinity chromatography purified
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Immunogen
- INSR antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
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Application Notes
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IHC-P: 10 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Concentration
- Lot specific
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Buffer
- Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
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- Insulin Receptor (INSR)
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Alternative Name
- INSR
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Background
- In molecular biology, the insulin receptor is a transmembrane receptor that is activated by insulin. It belongs to the large class of tyrosine kinase receptors. Two alpha subunits and two beta subunits make up the insulin receptor. The beta subunits pass through the cellular membrane and are linked by disulfide bonds. The alpha and beta subunits are encoded by a single gene.
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Pathways
- NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
Target
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