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ITGA2 antibody
ITGA2
Reactivity: Human
IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ITGA2 Antibody
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Target
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ITGA2
(Integrin alpha 2 (ITGA2))
Reactivity
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Human
Host
All hosts for ITGA2 antibodies
Rabbit
Clonality
All clonalities for ITGA2 antibodies
Polyclonal
Conjugate
All conjugates for ITGA2 antibodies
This ITGA2 antibody is un-conjugated
Application
All applications for ITGA2 antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
Affinity chromatography purified
Immunogen
CD49 B antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
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Application Details
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Application Notes
IHC-P: 10 µg/mL Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
Lot specific
Buffer
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
Target Details for ITGA2
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Target
ITGA2
(Integrin alpha 2 (ITGA2))
Alternative Name
CD49b (ITGA2 Products )
Synonyms
BR antibody, CD49B antibody, GPIa antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody, DX5 antibody, integrin subunit alpha 2 antibody, integrin alpha 2 antibody, ITGA2 antibody, Itga2 antibody
Background
The CD49b protein is an integrin alpha subunit. It makes up half of the alpha2Beta1 integrin duplex. Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. They are found on a wide variety of cell types including, T cells (the NKT cells), NK cells, fibroblasts and platelets. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling.
Pathways
CXCR4-mediated Signaling Events , Smooth Muscle Cell Migration , Integrin Complex
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