Annexin A2 antibody (N-Term)

Catalog No. ABIN639934

Product Details anti-Annexin A2 Antibody

Target: Annexin A2 (ANXA2)

Binding Specificity: N-Term

Reactivity: Human

Host: Goat

Conjugate: This Annexin A2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: DS-PB-00175 recognises Annexin II, a member of a family of structurally related calcium binding proteins implicated in mediating the intracellular action of calcium. Cellular levels of annexin II mRNA and protein are strictly regulated during the mammalian cell cycle with maximal expression as cells enter S-phase.

Characteristics: Goat Anti-Human Annexin II, N-terminus

Purification: Purified

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Reconstitution: Supplied as 0.1mg of purified liquid antibody in TBS, containing 0.02% Sodium azide and 0.5% Bovine serum albumin. Its final concentration is 0.5 mg/ml. Please avoid freeze-thaw cycles.

Storage: 4 °C

Target Details for Annexin A2

Target: Annexin A2 (ANXA2)

Alternative Name: Annexin II (ANXA2 Products)

Synonyms: ANX2 antibody, ANX2L4 antibody, CAL1H antibody, LIP2 antibody, LPC2 antibody, LPC2D antibody, P36 antibody, PAP-IV antibody, AW215814 antibody, Cal1h antibody, p36 antibody, anx2 antibody, lip2 antibody, lpc2 antibody, cal1h antibody, lpc2d antibody, pap-i antibody, anx2l4 antibody, MGC76145 antibody, ANXA2 antibody, anxa2 antibody, anxa2-a antibody, anxa2-b antibody, annexin A2 antibody, annexin A2 S homeolog antibody, ANXA2 antibody, Anxa2 antibody, anxa2 antibody, anxa2.S antibody

Background: The Annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner and a unique amino-terminal region which may confer binding specificity. The interaction between these proteins and biological membranes has led to the hypothesis that they are involved in cellular trafficking processes such as endocytosis, exocytosis and cellular adhesion. Annexin I, alternatively referred to as lipocortin, has been implicated as a mediator of the anti-inflammatory response produced by glucocorticoids and as an inhibitor of cPLA2, a potent mediator of inflammation. Annexin II, also called p36, exists as a monomer or as a heterotetramer, complexed with the S-100-related protein p11. This complex is termed calpactin I. In the tetrameric form, Annexin II is an efficient substrate of PKC family and Src pp60.

Pathways: S100 Proteins