IGF2 antibody

Catalog No. ABIN641010

Product Details anti-IGF2 Antibody

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Functional Studies (Func), Concentration (Conc)

Purpose: Rabbit Anti-Human Insulin-Like Growth Factor II, with HRP-conjugated Secondary Antibody

Specificity: DS-PB-01054 is specific for human IGF-II (Insulin-like Growth Factor II), a 67 amino acid mitogenic polypeptide and member of the Insulin gene family, synthesized by various foetal tissues during prenatal development, under the influence of placental lactogen. IGF-II is a growth factor which exhibits both paracrine and autocrine properties and signals by binding to the type 1 and type 2 insulin-like growth factor receptors (type 1 IGFR and type 2 IGFR), and also to the insulin receptor (IR). The availability of IGF-II is dependent upon its attachment to, and release from, various IGF binding proteins (IGFBPs), a relationship which has been investigated in breast cancer research (2).

Characteristics: Cytokines/Chemokines/Growth Factors/Receptors

Purification: Purified

Immunogen: Antisera to human IGF-II were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Isotype: IgG

Application Details

Application Notes: ELISA (recommended concentration: 0.5 - 2.0 µ,g/mL), Functional Assays (recommended concentration: 3.1 - 4.6 µ,g/mL), Western Blotting (recommended concentration: 0.1 - 0.2 µ,g/mL)

Restrictions: For Research Use only

Handling

Reconstitution: Reconstitute with 0.1 mL distilled water. For long term storage the addition of 0.09 % sodium azide is recommended.Note: For functional studies do not add azide.

Storage: -20 °C

Storage Comment: -20°C

Target Details for IGF2

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Alternative Name: Insulin-Like Growth Factor II (IGF2 Products)

Synonyms: C11orf43 antibody, IGF-II antibody, PP9974 antibody, LOC100136550 antibody, igf2 antibody, igf2b antibody, wu:fc26e03 antibody, zgc:91781 antibody, igf-2 antibody, insigf antibody, pp9974 antibody, AL033362 antibody, Igf-2 antibody, Igf-II antibody, M6pr antibody, Mpr antibody, Peg2 antibody, IGFII antibody, RNIGF2 antibody, IGF-II-B antibody, igf2-a antibody, igf2-b antibody, insulin like growth factor 2 antibody, insulin-like growth factor II antibody, insulin-like growth factor 2a antibody, insulin like growth factor 2 S homeolog antibody, insulin-like growth factor 2 antibody, insulin-like growth factor 2 (somatomedin A) antibody, insulin like growth factor 2 L homeolog antibody, IGF2 antibody, LOC100136550 antibody, igf2a antibody, igf2.S antibody, Igf2 antibody, igf2.L antibody

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation