VEGFR2/CD309 antibody

Catalog No. ABIN643552

This Rabbit Polyclonal antibody specifically detects VEGFR2/CD309 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for VEGFR2/CD309 antibody (ABIN643552)

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGFR2/CD309 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-VEGFR2/CD309 Antibody

Purpose: Rabbit Anti-Human VEGFR2

Specificity: DS-PB-02108 detects vascular endothelial growth factor receptor 2 (VEGFR2), a member of the tyrosine kinase family that plays an essential role in transducing the major signals for angiogenesis. VEGFR2 has also been implicated in embryonic development, wound healing, cell proliferation, migration and differentiation. VEGFR2 is expressed mostly on vascular endothelial cells, and is expressed on a subpopulation of haematopoietic cells which might be the progenitor for endothelial cells. Mutated forms of VEGFR2 have been implicated in cancer and diabetic retinopathy, where it results in pathological angiogenesis.

Characteristics: Cytokines/Chemokines/Growth Factors/Receptors

Purification: Purified

Immunogen: Antisera to human VEGF receptor 2 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Isotype: IgG

Application Details

Application Notes: Immunohistology - Paraffin

Restrictions: For Research Use only

Handling

Concentration: IgG concentration 0.5 mg/ml

Buffer: Phosphate buffered saline pH7.7

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for VEGFR2/CD309

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Alternative Name: Vascular Endothelial Growth Factor Receptor 2 (VEGF R2)

Pathways: RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling