SYK antibody

Catalog No. ABIN645841

Product Details anti-SYK Antibody

Target: SYK (Spleen tyrosine Kinase (SYK))

Reactivity: Human, Mouse, Rat

Host: Goat

Conjugate: This SYK antibody is un-conjugated

Application: Please inquire

Specificity: The Goat anti-Spleen tyrosine kinase / SYK antibody detects protein derived from human recombinant protein and human spleen lysate at various concentrations.

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Characteristics: Goat Anti-Spleen Tyrosine Kinase / SYK

Immunogen: Peptide with sequence C-KYLQQNRHVKDKN, from the internal region of the protein sequence according to NP_003168.2.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Reconstitution: Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Storage: -20 °C

Target Details for SYK

Target: SYK (Spleen tyrosine Kinase (SYK))

Alternative Name: Spleen Tyrosine Kinase / SYK (SYK Products)

Synonyms: p72-Syk antibody, Sykb antibody, p72syk antibody, spleen associated tyrosine kinase antibody, spleen tyrosine kinase antibody, syk antibody, SYK antibody, Syk antibody

Background: A member of the syk family of tyrosine kinases. The long isoform is composed of 635 amino acids(72 kDa). The short isoform is composed of 612 amino acids, and lacks part of the interdomain B. These non-receptor cytoplasmic tyrosine kinases share a characteristic dual SH2 domain separated by a an interdomain A, an interdomain B, and a protein kinase domain in C-term, and contains a number of autophosphorylation sites on tyrosines While syk are primarily expressed in hematopoietic tissues, there is expression of syk in a variety of tissues. Within B and T cells respectively, Syk transmit signals from the B-Cell receptor and T-Cell receptor.

NCBI Accession: NP_003168

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling