IRAK4 antibody (N-Term)

Catalog No. ABIN645843

Product Details anti-IRAK4 Antibody

Target: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Monkey

Host: Goat

Conjugate: This IRAK4 antibody is un-conjugated

Application: Please inquire

Specificity: The Goat Anti-IRAK4 (N Terminus) antibody detects protein derived from human recombinant protein and HELA lysate at various concentrations.

Cross-Reactivity: Human, Mouse (Murine), Monkey

Characteristics: Goat Anti-IRAK4 (N Terminus)

Immunogen: Peptide with sequence NKPITPSTYVRC, from the N Terminus of the protein sequence according to NP_057207.1.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Reconstitution: Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Minimize freezing and thawing cycles.

Storage: -20 °C

Target Details for IRAK4

Target: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Alternative Name: IRAK4 (IRAK4 Products)

Synonyms: zgc:55553 antibody, IRAK4 antibody, ipd1 antibody, irak-4 antibody, ny-ran-64 antibody, ny-ren-64 antibody, ren64 antibody, irak4 antibody, IPD1 antibody, IRAK-4 antibody, NY-REN-64 antibody, REN64 antibody, 8430405M07Rik antibody, 9330209D03Rik antibody, interleukin 1 receptor associated kinase 4 antibody, interleukin-1 receptor-associated kinase 4 antibody, IRAK4 antibody, irak4 antibody, Irak4 antibody

Background: Interleukin-1 receptor (see IL1R, MIM 147810)-associated kinases (e.g., IRAK1, MIM 300283) are important mediators in the signal transduction of Toll-like receptor (TLR, e.g., TLR4, MIM 603030) and IL1R family members, collectively referred to as TIRs. IRAK4 functions in this signal transduction pathway.

NCBI Accession: NP_057207

Pathways: NF-kappaB Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades