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VCAM1 antibody (FITC)

VCAM1 Reactivity: Human FACS, ICC Host: Mouse Monoclonal B-K9 FITC
Catalog No. ABIN6253936
  • Target See all VCAM1 Antibodies
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Reactivity
    • 134
    • 92
    • 55
    • 25
    • 15
    • 8
    • 8
    • 4
    • 3
    • 1
    Human
    Host
    • 95
    • 71
    • 29
    • 5
    • 1
    • 1
    Mouse
    Clonality
    • 109
    • 91
    • 1
    Monoclonal
    Conjugate
    • 92
    • 25
    • 23
    • 11
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VCAM1 antibody is conjugated to FITC
    Application
    • 114
    • 91
    • 52
    • 42
    • 33
    • 27
    • 27
    • 26
    • 21
    • 16
    • 14
    • 12
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Specificity
    B-K9 produces mouse IgG1 immunoglobulins directed against a 110 kD protein known as human CD106. It reacts with approximately 15% of peripheral lymphocytes and between 30-90% activated HUVEC
    Clone
    B-K9
    Isotype
    IgG1
    Top Product
    Discover our top product VCAM1 Primary Antibody
  • Application Notes
    tochemistry on cytospots,  immunohistochemistry on frozen tissue sections
    Restrictions
    For Research Use only
  • Format
    Liquid
    Storage
    4 °C
  • Target
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Alternative Name
    CD106 (VCAM1 Products)
    Synonyms
    CD106 antibody, INCAM-100 antibody, Vcam-1 antibody, VCAM1B antibody, fi76d06 antibody, wu:fi76d06 antibody, zgc:158875 antibody, VCAM1 antibody, vascular cell adhesion molecule 1 antibody, vascular cell adhesion molecule 1b antibody, VCAM1 antibody, Vcam1 antibody, vcam1b antibody, VCAM-1 antibody
    Background
    Antigen distribution: CD106 antigen binds the integrins a4b1 (CD49d/CD29, VLA-4) and a4b7 [4]. VLA-4 is the dominant ligand in cells expressing both integrins. Endothelial CD106 contributes to the extravasation of lymphocytes, monocytes, basophils and eosinophils (but not neutrophils) from blood vessels, especially at sites of inflammation. The VLA-4 interaction can mediate both the initial tethering and rolling of lymphocytes on endothelium as well as their subsequent arrest and firm adhesion [5]. CD106 expression on non-vascular tissues is thought to play a role in the interaction of hematopoietic progenitors with bone marrow stromal cells, B cell binding to follicular dendritic cells, co-stimulation of T cells and embryonic development [1,2,3]. Cellular Expression: VCAM-1. Vascular endothelium, dendritic cells, macrophages
    Pathways
    Carbohydrate Homeostasis
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