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FCER2 antibody (PE)

FCER2 Reactivity: Human FACS, ICC Host: Mouse Monoclonal B-G6 PE
Catalog No. ABIN6253877
  • Target See all FCER2 Antibodies
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    Reactivity
    • 92
    • 50
    • 11
    Human
    Host
    • 54
    • 44
    • 16
    Mouse
    Clonality
    • 70
    • 42
    • 2
    Monoclonal
    Conjugate
    • 54
    • 14
    • 9
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FCER2 antibody is conjugated to PE
    Application
    • 68
    • 51
    • 33
    • 20
    • 13
    • 10
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Specificity
    B-G6 produces mouse IgG1 immunoglobulins directed against CD23 antigen. It is suitable for use in flow cytometry and immunohistochemistry
    Clone
    B-G6
    Isotype
    IgG1
    Top Product
    Discover our top product FCER2 Primary Antibody
  • Application Notes
    immunohistochemistry on cytospots,  immunohistochemistry on frozen tissue
    Restrictions
    For Research Use only
  • Format
    Liquid
    Storage
    4 °C
  • Target
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    Alternative Name
    CD23 (FCER2 Products)
    Synonyms
    BLAST-2 antibody, CD23 antibody, CD23A antibody, CLEC4J antibody, FCE2 antibody, IGEBF antibody, Fcer2a antibody, Fc fragment of IgE receptor II antibody, FCER2 antibody, Fcer2 antibody
    Background
    Antigen distribution: CD23 is a low affinity receptor for IgE (FceR) and both the FceRIIa and FceRIIb are expressed on mature IgD+/IgM+ B cells. The FceRIIb form is also present on monocytes, activated macrophages, eosinophils, platelets and follicular dendritic cells [1]. CD23 is also present in a soluble form in serum [2]. CD23 together with CD19 and CD22, plays a role in the modulation of B cell activation through membrane immunoglobulin and is involved in regulation of IgE synthesis. Expression of CD23 is increased by IL-4 and down-regulated by B-cell growth factor (BCGF). Binding of IgE immune complexes to CD23 increases the efficiency of B cell antigen processing and presentation. Via its interaction with CD21 it may play a role in adhesion processes. It mediates IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils [3,4]. Cellular Expression: B cell differentiation antigen.
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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