Cofilin 1 (Non-Muscle) (CFL1) (AA 70-98), (Center) antibody

Details for Product No. ABIN650759
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Antigen
Synonyms
CFL, CFL1, AA959946, Cof, cfl1, xac1, xac2, cfl, cb86, sb:cb86, zgc:56501, wu:fb18a04, wu:fk77b03, 12/8, ADF, ADF/cofilin, Adf, CG4254, Cadf, D-cof, D61, Dmel\\CG4254, T8, Tsr, cofilin, cofilin/ADF, c ... show more
CFL, CFL1, AA959946, Cof, cfl1, xac1, xac2, cfl, cb86, sb:cb86, zgc:56501, wu:fb18a04, wu:fk77b03, 12/8, ADF, ADF/cofilin, Adf, CG4254, Cadf, D-cof, D61, Dmel\\CG4254, T8, Tsr, cofilin, cofilin/ADF, cofilin/actin depolymerizing factor homolog, l(2)03101, l(2)k03101, l(2)k05633, l(2)k13409, ntf show less
Epitope
AA 70-98, Center
(45), (21), (14), (12), (12), (8), (7), (4), (4), (4), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(210), (143), (138), (60), (52), (36), (28), (25), (12), (4)
Host
Rabbit
(183), (31), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5)
Application
Western Blotting (WB), Flow Cytometry (FACS)
(144), (78), (50), (50), (49), (25), (12), (5), (4), (3), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN650759
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This CFL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 AA from the Central region of human CFL1.
Clone RB23947
Isotype Ig
Specificity This CFL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77~106 amino acids from the Center region of human CFL1.
Predicted Reactivity Cow (Bovine),Chicken,Pig (Porcine),Monkey,Rat (Rattus),Xenopus laevis
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CFL1
Background Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner.
Synonyms: Cofilin-1, Cofilin, non-muscle isoform, 18 kDa phosphoprotein, p18, CFL, CFL1
Molecular Weight 18502 DA
Gene ID 1072
UniProt P23528
Research Area Stem Cells, Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Cofilin 1 (Non-Muscle) (CFL1) (AA 70-98), (Center) antibody Western blot analysis of CFL1 Antibody (Center) (ABIN650759) in HL-60 cell line lysates (35 µg/lane). CFL1 (arrow) was detected using the purified polyclonal antibody.
anti-Cofilin 1 (Non-Muscle) (CFL1) (AA 70-98), (Center) antibody (2) Western blot analysis of CFL1 Antibody (Center) (ABIN650759) in mouse NIH-3T3 cell line lysates (35 µg/lane). CFL1 (arrow) was detected using the purified polyclonal antibody.
anti-Cofilin 1 (Non-Muscle) (CFL1) (AA 70-98), (Center) antibody (3) CFL1 Antibody (Center) (ABIN650759) flow cytometric analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Fazal, Bijli, Minhajuddin et al.: "Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells." in: The Journal of biological chemistry, Vol. 284, Issue 31, pp. 21047-56, 2009 (PubMed).

Hosts (183), (31), (3)
Reactivities (210), (143), (138), (60), (52), (36), (28), (25), (12), (4)
Applications (144), (78), (50), (50), (49), (25), (12), (5), (4), (3), (2), (1)
Conjugates (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5)
Epitopes (45), (21), (14), (12), (12), (8), (7), (4), (4), (4), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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