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ABCC11 antibody (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11) (AA 343-372)

Details for Product anti-ABCC11 Antibody No. ABIN650984, Supplier: Log in to see
Antigen
  • EWWD
  • MRP8
  • WW
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 11
  • ABCC11
Epitope
AA 343-372, N-Term
12
8
8
7
4
3
3
3
2
1
1
1
1
1
1
1
1
Reactivity
Human
72
4
4
3
2
2
1
Host
Rabbit
37
26
7
3
Clonality (Clone)
Polyclonal ()
Conjugate
This ABCC11 antibody is un-conjugated
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
61
41
23
5
3
3
2
2
1
1
Options
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Immunogen This ABCC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-372 AA from the N-terminal region of human ABCC11.
Clone RB23836
Isotype Ig
Specificity This ABCC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350~380 amino acids from the N-terminal region of human ABCC11.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ABCC11 (ABCC11 Antibody Abstract)
Background ABCC11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1.
Synonyms: Multidrug resistance-associated protein 8, ATP-binding cassette transporter sub-family C member 11,MRP8, ABCC11
Molecular Weight 154301 DA
Gene ID 85320
UniProt Q96J66
Research Area Cell Structure, Protein Modifications, Chromatin, Signaling
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-ABCC11 antibody (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11) (AA 343-372) (ABIN650984) Western blot analysis of ABCC11 Antibody (N-term) (ABIN650984) in WiDr cell line lysa...
Immunohistochemistry (IHC) image for anti-ABCC11 antibody (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11) (AA 343-372) (ABIN650984) ABCC11 Antibody (N-term) (ABIN650984) IHC analysis in formalin fixed and paraffin emb...
Background publications Sato, Amano, Ono, Ishida, Kodera, Matsumura, Yoneda, Masuda: "Allele frequencies of the ABCC11 gene for earwax phenotypes among ancient populations of Hokkaido, Japan." in: Journal of human genetics, Vol. 54, Issue 7, pp. 409-13, 2009 (PubMed).