This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GABRG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-29 amino acids from the N-terminal region of human GABRG3.
GABRG3 antibody, B230362M20Rik antibody, Gabrg-3 antibody, gamma-aminobutyric acid type A receptor gamma3 subunit antibody, gamma-aminobutyric acid receptor subunit gamma-3 antibody, gamma-aminobutyric acid type A receptor gamma 3 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3 antibody, GABRG3 antibody, gabrg3 antibody, LOC100011485 antibody, Gabrg3 antibody
Background
GABRG3 is a family of proteins involved in the GABAergic neurotransmission of the mammalian central nervous system. GABRG3 is a member of the GABA-A receptor gene family of heteromeric pentameric ligand-gated ion channels through which GABA, the major inhibitory neurotransmitter in the mammalian brain, acts. GABA-A receptors are the site of action of a number of important pharmacologic agents including barbiturates, benzodiazepines, and ethanol (summary by Whiting et al., 1999 [PubMed 10414349]). For additional general information about the GABA-A receptor gene family, see GABRA1 (MIM 137160).