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AFT1 antibody (Activating Transcription Factor 1) (AA 193-219)

Details for Product anti-AFT1 Antibody No. ABIN651055, Supplier: Log in to see
Antigen
  • ews-atf1
  • fus/atf-1
  • treb36
  • ATF1
  • EWS-ATF1
  • FUS/ATF-1
  • TREB36
  • Atf-1
  • wu:fc92c07
  • zgc:64099
Alternatives
anti-Human AFT1 antibody for Western Blotting
Epitope
AA 193-219, C-Term
24
23
10
7
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
131
53
30
8
3
3
2
2
1
1
Host
Rabbit
111
22
2
1
Clonality (Clone)
Polyclonal ()
Conjugate
This AFT1 antibody is un-conjugated
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
112
62
26
23
16
13
13
7
4
2
1
1
1
1
Supplier
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Immunogen This ATF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-219 AA from the C-terminal region of human ATF1.
Clone RB22228
Isotype Ig
Specificity This ATF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ATF1.
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ATF1 (AFT1 Antibody Abstract)
Background ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.
Synonyms: Protein TREB36, Activating transcription factor 1, Cyclic AMP-dependent transcription factor ATF-1, cAMP-dependent transcription factor ATF-1,ATF1
Molecular Weight 29233 DA
Gene ID 466
UniProt P18846
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Cancer, Transcription Factors, Chromatin, Signaling, Cell Structure
Pathways Neurotrophin Signaling Pathway
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-AFT1 antibody (Activating Transcription Factor 1) (AA 193-219) (ABIN651055) Western blot analysis of ATF1 Antibody (C-term) (ABIN651055) in Jurkat cell line lysa...
Flow Cytometry (FACS) image for anti-AFT1 antibody (Activating Transcription Factor 1) (AA 193-219) (ABIN651055) ATF1 Antibody (C-term) (ABIN651055) flow cytometric analysis of Jurkat cells (right h...
Background publications Vega, Salas, Milne et al.: "Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study." in: Gynecologic oncology, Vol. 112, Issue 1, pp. 210-4, 2008 (PubMed).

Zheng, Cho, Lau et al.: "Cyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformation." in: Cancer research, Vol. 68, Issue 18, pp. 7650-60, 2008 (PubMed).