MAP3K11 antibody

Catalog No. ABIN651367

This Rabbit Polyclonal antibody specifically detects MAP3K11 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for MAP3K11 antibody (ABIN651367)

Target: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K11 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB22172

Product Details anti-MAP3K11 Antibody

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MAP3K11 antibody is generated from rabbits immunized with MAP3K11 recombinant protein.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for MAP3K11

Target: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Alternative Name: MAP3K11

Background: MAP3K11 is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.

Molecular Weight: 92688

Gene ID: 4296

NCBI Accession: NP_002410

UniProt: Q16584

Pathways: MAPK Signaling, Interferon-gamma Pathway