MAP3K11 antibody (AA 140-260)

Catalog No. ABIN7268648

The Rabbit Polyclonal anti-MAP3K11 antibody is suitable to detect MAP3K11 in samples from Human. It has been validated for WB.

Quick Overview for MAP3K11 antibody (AA 140-260) (ABIN7268648)

Target: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAP3K11 Antibody

Binding Specificity: AA 140-260

Purpose: MAP3K11 Rabbit pAb

Sequence: LVAVKAARQD PDEDISVTAE SVRQEARLFA MLAHPNIIAL KAVCLEEPNL CLVMEYAAGG PLSRALAGRR VPPHVLVNWA VQIARGMHYL HCEALVPVIH RDLKSNNILL LQPIESDDME H

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 140-260 of human MAP3K11 (NP_002410.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MAP3K11

Target: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Alternative Name: MAP3K11

Background: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.,MAP3K11,MEKK11,MLK-3,MLK3,PTK1,SPRK,Signal Transduction,Kinase,Serine/threonine kinases,Tyrosine kinases,MAPK-JNK Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,MAP3K11

Molecular Weight: 65kDa/92kDa

Gene ID: 4296

UniProt: Q16584

Pathways: MAPK Signaling, Interferon-gamma Pathway