Epidermal Growth Factor Receptor (EGFR) (C-Term), (AA 1004-1033) antibody

Details for Product No. ABIN651628
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Antigen
Synonyms
C-erb, CG10079, D-EGFR, D-Egf, DEGFR, DER, DER flb, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DER1, DEgfr, Degfr, Der, DmHD-33, Dmel\\CG10079, EFG-R, EGF-R, EGFR, EGFr, EGfr, EK2-6, Egf,  ... show more
C-erb, CG10079, D-EGFR, D-Egf, DEGFR, DER, DER flb, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DER1, DEgfr, Degfr, Der, DmHD-33, Dmel\\CG10079, EFG-R, EGF-R, EGFR, EGFr, EGfr, EK2-6, Egf, Egf-r, EgfR, El, Elp, Elp-1, Elp-B1, Elp-B1RB1, HD-33, TOP, Torpedo/DER, Torpedo/Egfr, c-erbB, d-egf-r, dEGFR, dEGFR1, dEgfr, der, egfr, flb, l(2)05351, l(2)09261, l(2)57DEFa, l(2)57EFa, l(2)57Ea, mor1, top, top/DER, top/flb, torpedo/Egfr, torpedo/egfr, EGFR12, EGFR15, egfr1, Erbb2, ERBB, ERBB1, HER1, PIG61, mENA, ErbB-1, Errp, 9030024J15Rik, AI552599, Erbb, Errb1, Wa5, wa-2, wa2 show less
Epitope
C-Term, AA 1004-1033
(90), (58), (52), (48), (47), (44), (43), (41), (41), (39), (38), (28), (25), (23), (20), (20), (18), (17), (17), (17), (17), (15), (15), (13), (13), (13), (13), (13), (12), (12), (10), (9), (9), (8), (8), (8), (8), (8), (7), (7), (7), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(1435), (673), (621), (160), (145), (124), (77), (7), (6), (3), (2), (1)
Host
Rabbit
(1129), (281), (22), (14), (8), (1), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(72), (47), (36), (26), (25), (25), (25), (25), (25), (25), (25), (19), (10), (10), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(966), (431), (309), (249), (243), (173), (145), (141), (95), (70), (53), (19), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
Quantity 400 μL
Options
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Catalog No. ABIN651628
238.50 $
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Immunogen This EGFR-S1026 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1004-1033 AA from the C-terminal region of human EGFR-S1026.
Clone RB26905
Isotype Ig
Specificity This EGFR-S1026 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1010-1029 amino acids from the C-terminal region of human IPO8.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name EGFR
Background The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Synonyms: EGFR,ERBB1
Molecular Weight 134277 DA
Gene ID 1956
NCBI Accession NP_005219, NP_958439, NP_958440, NP_958441
UniProt P00533
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications, Cancer, Chromatin, Signaling
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Epidermal Growth Factor Receptor (EGFR) (C-Term), (AA 1004-1033) antibody EGFR-S1026 (ABIN651628) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the EGFR antibody detected the EGFR protein (arrow).
anti-Epidermal Growth Factor Receptor (EGFR) (C-Term), (AA 1004-1033) antibody (2) EGFR-S1026 Antibody (C-term) (ABIN651628) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining..
anti-Epidermal Growth Factor Receptor (EGFR) (C-Term), (AA 1004-1033) antibody (3) EGFR-S1026 Antibody (C-term) (ABIN651628) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Lowenstein, Daly, Batzer et al.: "The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling." in: Cell, Vol. 70, Issue 3, pp. 431-42, 1992 (PubMed).

Validation Images
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