SRY (Sex Determining Region Y)-Box 2 (SOX2) (C-Term), (AA 227-262) antibody

Details for Product No. ABIN651838
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Antigen
Synonyms Qscn6, Qsox, Sox-2, rSOx, ANOP3, MCOPS3, RGD1565646, SRY-box2, Xsox-2, anop3, mcops3, sox-2, lcc, ysb, cb236, wu:fb83g04, wu:fc14d07, zgc:65860, zgc:77389
Epitope
C-Term, AA 227-262
(42), (9), (8), (7), (7), (6), (6), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(196), (66), (45), (21), (20), (20), (16), (12), (5), (4), (4), (3), (2), (2), (1), (1), (1)
Host
Rabbit
(159), (43), (5)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(11), (6), (6), (6), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(144), (74), (39), (34), (31), (29), (26), (24), (10), (10), (8), (3), (1)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN651838
291.50 $
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Immunogen This Sox2-pS246-pS249-pS250--pS251 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-262 AA from the C-terminal region of human Sox2-pS246-pS249-pS250--pS251.
Clone RB27268
Isotype Ig
Specificity This Sox2-pS246-pS249-pS250--pS251 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-260 amino acids from the C-terminal region of human Sox2.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SOX2
Background This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach.
Synonyms: Transcription factor SOX-2,SOX2,
Molecular Weight 34310 DA
Gene ID 6657
NCBI Accession NP_003097
UniProt P48431
Research Area Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (C-Term), (AA 227-262) antibody SOX2-pS246-pS249-pS250--pS251 Antibody (ABIN651838) western blot analysis in 293,CEM cell line lysates (15 µg/lane). This demonstrates the Sox2 antibody detected the Sox2 protein (arrow).
Background publications Laga, Lai, Zhan et al.: "Expression of the embryonic stem cell transcription factor SOX2 in human skin: relevance to melanocyte and merkel cell biology." in: The American journal of pathology, Vol. 176, Issue 2, pp. 903-13, 2010 (PubMed).

Validation Images
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