This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This WNT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 amino acids from the Central region of human WNT4.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze-thaw cycles.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
Expiry Date
6 months
Fang, Zeng, Wang, Liu, Xu, Dai, Zhao, Zhang, Liang, Chen, Shi, Zhang, Wang, Qiao, Shi: "Estimated diversity of messenger RNAs in each murine spermatozoa and their potential function during early zygotic development." in: Biology of reproduction, Vol. 90, Issue 5, pp. 94, (2014) (PubMed).
Target
WNT4
(Wingless-Type MMTV Integration Site Family, Member 4 (WNT4))
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Background
The WNT family consists of secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT4 is a protein which shows 98 % amino acid identity to the Wnt4 protein of mouse and rat. It play a concerted role in both the control of female development and the prevention of testes formation.