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Details for Product No. ABIN652493

BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 134-160), (Center) antibody

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Antigen
Synonyms BAM, BIM, BOD, Bim, Bod, 1500006F24Rik, BimL, bim
Epitope
»Alternatives AA 134-160, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN652493
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This BCL2L11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-160 AA from the Central region of human BCL2L11.
Clone RB22105
Isotype Ig
Specificity This BCL2L11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140~169 amino acids from the Center region of human BCL2L11.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BCL2L11
Background BCL2L11 belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator.
Synonyms: Bcl-2-like protein 11, Bcl2-L-11, Bcl2-interacting mediator of cell death, BIM, BCL2L11
Molecular Weight 22171 DA
Gene ID 10018
UniProt O43521
Research Area Apoptosis/Necrosis, Neurology
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.39 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Putcha, Le, Frank et al.: "JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis." in: Neuron, Vol. 38, Issue 6, pp. 899-914, 2003 (PubMed).

Hippe, Weber, Zhou et al.: "Toxoplasma gondii infection confers resistance against BimS-induced apoptosis by preventing the activation and mitochondrial targeting of pro-apoptotic Bax." in: Journal of cell science, Vol. 122, Issue Pt 19, pp. 3511-21, 2009 (PubMed).

Alternatives for antigen "BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)", type "Antibodies"
Hosts (151), (15), (12), (7), (3)
Reactivities (168), (129), (107), (37), (36), (24), (2), (1), (1)
Applications (124), (56), (47), (40), (37), (32), (19), (19), (16), (5), (5), (3), (3), (3)
Conjugates (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Epitopes (21), (15), (12), (12), (9), (8), (4), (4), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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