anti-BIM antibody (BCL2-Like 11 (Apoptosis Facilitator)) (AA 134-160)

Details for Product anti-BCL2L11 Antibody No. ABIN652493
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Antigen
Synonyms bim, BAM, BIM, BOD, 1500006F24Rik, Bim, Bod, BimL, BIMEL
Epitope
AA 134-160, Center
(81), (28), (15), (15), (12), (12), (12), (12), (9), (8), (8), (7), (7), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(307), (161), (123), (2)
Host
Rabbit
(274), (24), (19), (17), (7)
Clonality (Clone)
Polyclonal ()
Conjugate
This BIM antibody is un-conjugated
(19), (17), (10), (10), (9), (9), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(251), (145), (109), (52), (42), (36), (33), (31), (16), (13), (9), (4), (3), (3), (3), (3)
Pubmed 2 references available
Quantity 400 μL
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Immunogen This BCL2L11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-160 AA from the Central region of human BCL2L11.
Clone RB22105
Isotype Ig
Specificity This BCL2L11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140~169 amino acids from the Center region of human BCL2L11.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BCL2L11 (BCL2L11 Antibody Abstract)
Background BCL2L11 belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator.
Synonyms: Bcl-2-like protein 11, Bcl2-L-11, Bcl2-interacting mediator of cell death, BIM, BCL2L11
Molecular Weight 22171 DA
Gene ID 10018
UniProt O43521
Research Area Apoptosis/Necrosis, Neurology
Pathways PI3K-Akt Signaling Pathway
Application Notes WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.39 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 134-160), (Center) antibody Western blot analysis of BCL2L11 Antibody (Center) (ABIN652493) in K562, HL-60 cell l...
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 134-160), (Center) antibody (2) Formalin-fixed and paraffin-embedded human colon carcinoma reacted with BCL2L11 Antib...
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 134-160), (Center) antibody (3) Flow cytometric analysis of WiDr cells using BCL2L11 Antibody (Center)(bottom histogr...
Background publications Hippe, Weber, Zhou et al.: "Toxoplasma gondii infection confers resistance against BimS-induced apoptosis by preventing the activation and mitochondrial targeting of pro-apoptotic Bax." in: Journal of cell science, Vol. 122, Issue Pt 19, pp. 3511-21, 2009 (PubMed).

Putcha, Le, Frank et al.: "JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis." in: Neuron, Vol. 38, Issue 6, pp. 899-914, 2003 (PubMed).

Validation Images
Catalog No. ABIN652493
291.50 $
Plus shipping costs $45.00
Quantity
Price
400 μL
291.50 $

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