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Transcription Factor A, Mitochondrial (TFAM) (AA 216-246), (C-Term) antibody

Details for Product No. ABIN654229, Supplier: Log in to see
Antigen
  • tcf6
  • mttf1
  • mttfa
  • tcf6l1
  • tcf6l2
  • tcf6l3
  • mttfa-A
  • xl-mtTFA
  • MGC153358
  • zgc:153358
  • MTTF1
  • MTTFA
  • TCF6
  • TCF6L1
  • TCF6L2
  • TCF6L3
  • AI661103
  • Hmgts
  • mtTFA
  • tsHMG
  • Mttfa
Epitope
AA 216-246, C-Term
24
16
8
6
6
6
5
5
3
3
3
2
2
2
1
1
1
1
1
Reactivity
Human
90
30
29
2
1
1
Host
Rabbit
110
2
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
6
6
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
72
45
45
33
20
18
16
11
6
5
4
2
Supplier
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Immunogen This TFAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-246 AA from the C-terminal region of human TFAM.
Clone RB27631
Isotype Ig
Specificity This TFAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-254 amino acids from the C-terminal region of human TFAM.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name TFAM (TFAM Antibody Abstract)
Background This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.
Synonyms: Transcription factor A, mitochondrial,TFAM,TCF6, TCF6L2
Molecular Weight 29097 DA
Gene ID 7019
NCBI Accession NP_003192
UniProt Q00059
Research Area Translation Factors, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes IHC (p) = 1:50-100, FACS = 1:10-50, IF = 1:10-50, WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-Transcription Factor A, Mitochondrial (TFAM) (AA 216-246), (C-Term) antibody (ABIN654229) TFAM antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin ...
Flow Cytometry (FACS) image for anti-Transcription Factor A, Mitochondrial (TFAM) (AA 216-246), (C-Term) antibody (ABIN654229) TFAM Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) comp...
Immunofluorescence (IF) image for anti-Transcription Factor A, Mitochondrial (TFAM) (AA 216-246), (C-Term) antibody (ABIN654229) Fluorescent confocal image of NCI-H460 cell stained with TFAM Antibody (C-term). NCI-...
Western Blotting (WB) image for anti-Transcription Factor A, Mitochondrial (TFAM) (AA 216-246), (C-Term) antibody (ABIN654229) TFAM Antibody (C-term) western blot analysis in Hela,Jurkat,K562,MCF-7 cell line lys...
Background publications Shulman, Chibnik, Aubin et al.: "Intermediate phenotypes identify divergent pathways to Alzheimer's disease." in: PLoS ONE, Vol. 5, Issue 6, pp. e11244, 2010 (PubMed).