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Details for Product No. ABIN654605

APG8a/b (MAP1LC3A/B) (AA 100-125), (cleaved) antibody

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Antigen
Epitope
AA 100-125, cleaved
Reactivity
Human, Mouse (Murine)
Host
Rabbit
Clonality (Clone) Polyclonal ()
Application
Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN654605
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This Cleaved-APG8a/b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-125 AA from human Cleaved-APG8a/b.
Clone RB28610
Isotype Ig
Specificity This Cleaved-APG8a/b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from human Cleaved-APG8a/b.
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Background The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
Synonyms: MAP1LC3B,Microtubule-associated proteins 1A/1B light chain 3B,MAP1ALC3
Molecular Weight 14688 DA
Gene ID 81631
UniProt Q9GZQ8, NP_073729.1
Research Area Cell Structure, Autophagy
Application Notes Recommend dilutions: IF : 1:100,WB : 1:1000,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.29 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Kirkin, Lamark, Sou et al.: "A role for NBR1 in autophagosomal degradation of ubiquitinated substrates." in: Molecular cell, Vol. 33, Issue 4, pp. 505-16, 2009 (PubMed).

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