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SEL1L antibody (Sel-1 Suppressor of Lin-12-Like (C. Elegans)) (AA 156-182)

Details for Product anti-SEL1L Antibody No. ABIN654642, Supplier: Log in to see
Antigen
  • SEL1L
  • MGC99195
  • PRO1063
  • SEL1-LIKE
  • SEL1L1
  • AW493766
  • Sel1h
  • mKIAA4137
  • Sel-1L
Epitope
AA 156-182, Center
25
18
16
16
8
2
1
1
Reactivity
Human
67
17
17
3
2
1
1
1
1
Host
Rabbit
51
15
2
Clonality (Clone)
Polyclonal ()
Conjugate
This SEL1L antibody is un-conjugated
6
6
6
5
5
5
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
53
42
16
14
11
6
3
2
1
Supplier
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Immunogen This SEL1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-182 AA from the Central region of human SEL1L.
Clone RB28451
Isotype Ig
Specificity This SEL1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-186 amino acids from the Central region of human SEL1L.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SEL1L (SEL1L Antibody Abstract)
Background May play a role in Notch signaling (By similarity). May be involved in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.
Synonyms: Protein sel-1 homolog 1,SEL1L,TSA305
Molecular Weight 88755 DA
Gene ID 6400
NCBI Accession NP_005056
UniProt Q9UBV2
Research Area Cell Signaling, Protein Modifications, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Flow Cytometry (FACS) image for anti-SEL1L antibody (Sel-1 Suppressor of Lin-12-Like (C. Elegans)) (AA 156-182) (ABIN654642) SEL1L Antibody (Center) (ABIN654642) flow cytometric analysis of MCF-7 cells (right h...
Background publications Riemer, Appenzeller-Herzog, Johansson et al.: "A luminal flavoprotein in endoplasmic reticulum-associated degradation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 35, pp. 14831-6, 2009 (PubMed).

Cormier, Tamura, Sunryd et al.: "EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex." in: Molecular cell, Vol. 34, Issue 5, pp. 627-33, 2009 (PubMed).