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Achaete-Scute Complex Homolog 2 (Drosophila) (ASCL2) (N-Term), (AA 38-65) antibody

Details for Product No. ABIN654929
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Antigen
Synonyms mash2, ascl2, ASCL2, MASH2, 2410083I15Rik, Mash2, bHLHa45, ASH2, HASH2, ASH2L1, ASH2L2, Bre2
Epitope
N-Term, AA 38-65
(9), (8), (6), (4), (2)
Reactivity
Human, Mouse (Murine)
(34), (22), (18), (15), (15), (14), (13), (1), (1), (1)
Host
Rabbit
(33), (3), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(27), (10), (10), (3), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN654929
291.50 $
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Immunogen This ASCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-65 AA from the N-terminal region of human ASCL2.
Clone RB24666
Isotype Ig
Specificity This ASCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-65 amino acids from the N-terminal region of human ASCL2.
Predicted Reactivity Cow (Bovine),Rat (Rattus),Xenopus laevis,Zebrafish
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ASCL2
Background This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
Synonyms: Achaete-scute homolog 2,ASCL2,BHLHA45, HASH2
Molecular Weight 20185 DA
Gene ID 430
UniProt NP_005161.1, Q99929
Research Area Cell Cycle, Transcription Factors, Signaling, Neurology, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Achaete-Scute Complex Homolog 2 (Drosophila) (ASCL2) (N-Term), (AA 38-65) antibody ASCL2 Antibody (N-term) (ABIN654929) western blot analysis in mouse bladder tissue lysates (35 µg/lane). This demonstrates the ASCL2 antibody detected the ASCL2 protein (arrow).
Background publications Barrett, Clayton, Concannon et al.: "Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes." in: Nature genetics, Vol. 41, Issue 6, pp. 703-7, 2010 (PubMed).

Validation Images
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