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Details for Product No. ABIN655663

Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1) (AA 66-93), (Center) antibody

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Antigen
Synonyms ID, bHLHb24, Idb1, AI323524, D2Wsu140e, ID125A, ID1, id6, cb108, wu:fb57e11
Epitope
»Alternatives AA 66-93, Center
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN655663
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This ID1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-93 AA from the Central region of human ID1.
Clone RB29169
Isotype Ig
Specificity This ID1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-101 amino acids from the Central region of human ID1.
Predicted Reactivity Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ID1
Background The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Synonyms: RB29238
Molecular Weight 16133 DA
Gene ID 3397
UniProt NP_851998.1, NP_002156.2, P41134
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50,IF : 1:10-50,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Qian, Lee, Park et al.: "Id1 enhances RING1b E3 ubiquitin ligase activity through the Mel-18/Bmi-1 polycomb group complex." in: Oncogene, Vol. 29, Issue 43, pp. 5818-27, 2010 (PubMed).

Hamajima, Komori, Preciado et al.: "The role of inhibitor of DNA-binding (Id1) in hyperproliferation of keratinocytes: the pathological basis for middle ear cholesteatoma from chronic otitis media." in: Cell proliferation, Vol. 43, Issue 5, pp. 457-63, 2010 (PubMed).

Alternatives for antigen "Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1)", type "Antibodies"
Hosts (32), (19)
Reactivities (49), (28), (26), (24), (24), (12), (12)
Applications (31), (25), (20), (8), (7), (2), (2), (2), (1), (1), (1), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (11), (3), (1), (1), (1), (1)
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